FISH-ing Novel Dynamic Modes of Glucocorticoid-Induced Chromatin Reorganization.

Trends Endocrinol Metab

University of Bristol, Translational Health Sciences, Dorothy Hodgkin Building, Whitson Street, Bristol BS13NY, UK. Electronic address:

Published: April 2018

In a recent study, Jubb et al. used 3D DNA FISH to assess glucocorticoid-induced 'chromatin decompaction' at multiple loci. Determinants of the specificity, speed, and duration of this phenomenon further enhance our understanding of how the glucocorticoid receptor (GR) dynamically alters chromatin accessibility during acute-phase transcriptional regulation and beyond.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tem.2018.02.003DOI Listing

Publication Analysis

Top Keywords

fish-ing novel
4
novel dynamic
4
dynamic modes
4
modes glucocorticoid-induced
4
glucocorticoid-induced chromatin
4
chromatin reorganization
4
reorganization study
4
study jubb
4
jubb dna
4
dna fish
4

Similar Publications

FISH-ing Novel Dynamic Modes of Glucocorticoid-Induced Chromatin Reorganization.

Trends Endocrinol Metab

April 2018

University of Bristol, Translational Health Sciences, Dorothy Hodgkin Building, Whitson Street, Bristol BS13NY, UK. Electronic address:

In a recent study, Jubb et al. used 3D DNA FISH to assess glucocorticoid-induced 'chromatin decompaction' at multiple loci. Determinants of the specificity, speed, and duration of this phenomenon further enhance our understanding of how the glucocorticoid receptor (GR) dynamically alters chromatin accessibility during acute-phase transcriptional regulation and beyond.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!