AI Article Synopsis
- - The study investigates the link between C-reactive protein (CRP) levels and long-term mortality after acute myocardial infarction (AMI) in diabetic and non-diabetic patients.
- - A total of 2,516 patients (663 diabetic and 1,853 non-diabetic) were followed for an average of 2.9 years, with findings showing that higher CRP levels indicated increased mortality risk in both groups.
- - CRP proved to be an independent predictor of long-term mortality outcomes, including all-cause, cardiovascular, and cardiac mortality, regardless of diabetes status.
Article Abstract
Background: Little is known about the relationship between C-reactive protein (CRP) and long-term mortality after acute myocardial infarction (AMI) in diabetic patients. The current study aimed to examine whether CRP levels are associated with for long-term all-cause, cardiovascular, and cardiac mortality in AMI patients with diabetes and those without separately.
Methods: The cohort study included 663 diabetic and 1853 non-diabetic patients with AMI. The median follow-up time was 1045 days (2.9 years).
Results: According to the median concentration of serum CRP (8.95 mg/l), the patients were divided into two groups. The low CRP level group (<8.95 mg/l) served as a reference. In diabetic patients with AMI, the adjusted hazard ratios (HRs) for long-term all-cause, cardiovascular, and cardiac mortality were 1.62 (P = 0.027), 1.91 (P = 0.008), and 2.08 (P = 0.007), respectively. In non-diabetic patients with AMI, the adjusted hazard ratios (HRs) for long-term all-cause, cardiovascular, and cardiac mortality were 1.72 (P < 0.001), 1.8 (P < 0.001), and 1.78 (P = 0.001), respectively.
Conclusions: Regardless of whether patients had diabetes or not, CRP value is an independent predictor of long-term, all-cause, cardiovascular, and cardiac mortality after AMI.
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| http://dx.doi.org/10.1016/j.cca.2018.02.025 | DOI Listing |
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