AI Article Synopsis
- Low or absent immunoglobulin A (IgA) levels are commonly observed in children without suspected immunodeficiency and IgA deficiency is the most common primary immunodeficiency disorder in the UK, affecting about 1 in 600 individuals.
- Isolated IgA deficiency is often discovered incidentally during examinations for other health issues like coeliac disease.
- The article aims to outline a systematic method for understanding the history, investigation, and treatment of isolated IgA deficiency.
Article Abstract
Low or absent immunoglobulin A (IgA) levels are frequently found in children in whom immunodeficiency is not suspected. IgA deficiency is the most common primary immunodeficiency disorder in the UK affecting approximately 1 in 600 people. Isolated IgA deficiency is often identified coincidentally when investigating a child for conditions such as coeliac disease. The aim of this article is to provide a structured approach to the history, investigation and management of an isolated IgA deficiency.
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| http://dx.doi.org/10.1136/archdischild-2016-312386 | DOI Listing |
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