Objective: In the current study, we investigated whether there are relations among depressive symptoms, cognitive performance and serum BDNF levels in the patients with chronic kidney disease (CKD).
Methods: Sixty patients with CKD and 65 healthy controls participated. Depressive symptoms were evaluated with Beck depression inventory (BDI) and Hamilton Depression Rating Scale (HDRS). Mini-Mental State Examination included in the Korean version of the Consortium to Establish a Registry for Alzheimer's disease (MMSE-KC) assessment packet was used for the evaluation of overall cognitive function. To assess memory function, the Korean version of the Hopkins Verbal Learning Test (K-HVLT) was used. BDNF levels were measured using an enzyme-linked immunosorbent assay (ELISA) kit.
Results: The CKD patients showed more depressive symptoms when compared with controls. The depressive symptoms and cognitive function were not associated with serum BDNF levels in the CKD patients.
Conclusion: In the current study, CKD patients had more depressive symptoms when compared controls. However, the serum BDNF levels of CKD patients were not associated with depressive symptoms and cognitive functions. These findings suggested that the serum BDNF levels may not be reflect the cognitive function and depressive mood state in the CKD patients.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900401 | PMC |
| http://dx.doi.org/10.30773/pi.2017.03.09 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Long-term Effects of Local Area New Deal Work Relief in Childhood on Late Life Depression.
J Gerontol B Psychol Sci Soc Sci
December 2024
Department of Epidemiology and Population Health, Stanford University, Stanford, CA, USA.
Objective: To investigate whether childhood exposure to local area New Deal emergency employment work relief activity was associated with lower depressive symptoms in late life.
Methods: This study utilized individual-level data from the Wisconsin Longitudinal Study (WLS) linked to the full count 1940 census. New Deal emergency employment programs were the largest non-wartime expansion in government led infrastructure, services, and employment policy in U.
Positive dementia caregiving in 30 days (PDC30): Study protocol of a randomized controlled trial of a self-guided automated online training program.
Appl Psychol Health Well Being
February 2025
Department of Computing and Department of Rehabilitation Sciences, Hong Kong Polytechnic University, Hong Kong.
The Benefit-Finding Intervention, a face-to-face psychoeducation program with a focus on the positive meanings of caregiving, has been found to reduce depressive symptoms and burden in dementia caregivers. The program was revamped into a computer-delivered web-based program to enable 24/7 access without location restriction. This study evaluates the efficacy of this new online program called Positive Dementia Caregiving in 30 Days (PDC30).
View Article and Find Full Text PDFScreening for Depression and Anxiety Using a Nonverbal Working Memory Task in a Sample of Older Brazilians: Observational Study of Preliminary Artificial Intelligence Model Transferability.
JMIR Form Res
December 2024
thymia, International House, 64 Nile Street, London, N1 7SR, United Kingdom, 44 7477285252.
Background: Anxiety and depression represent prevalent yet frequently undetected mental health concerns within the older population. The challenge of identifying these conditions presents an opportunity for artificial intelligence (AI)-driven, remotely available, tools capable of screening and monitoring mental health. A critical criterion for such tools is their cultural adaptability to ensure effectiveness across diverse populations.
View Article and Find Full Text PDFTraditional Chinese medicine treatment of insomnia based on microbial-gut-brain axis theory.
World J Clin Cases
December 2024
Department of Neurosurgery, The Second Affiliated Hospital of Nantong University, Nantong 226000, Jiangsu Province, China.
In recent years, insomnia has gradually become a common disease in society, which seriously affects people's quality of life. At present, with the deepening of research on intestinal microbiota-gut-brain axis in Western medicine, many studies suggest that regulating the gastrointestinal tract can treat brain-related diseases. It is found that brain-gut-bacteria axis plays an important role in the prevention and treatment of primary insomnia.
View Article and Find Full Text PDFMerits and demerits of administering esketamine in preventing postpartum depression following cesarean section.
World J Clin Cases
December 2024
Department of Psychiatric Internal Medicine, Sunlight Brain Research Center, Hofu 7470066, Yamaguchi, Japan.
Emergency cesarean section is associated with the development of postpartum depression. Esketamine has been demonstrated to have a rapid onset of antidepressant effects. Randomized controlled trials and meta-analyses have demonstrated the efficacy of esketamine in preventing postpartum depression after cessarean section.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!