Five previously undescribed triterpenoid saponins (-), along with eight known ones (-), were isolated from the whole plants of var. . Their structures were clarified by extensive spectroscopic data and chemical evidence. For the first time, the lupane-type saponins ( and ) were reported from the genus. The anti-proliferative activity of all isolated saponins was evaluated on hepatic stellate cells (HSC-T6). Saponins and , which possess more monosaccharides than the others, displayed potent anti-proliferative activity, with IC values of 18.21 and 15.56 μM, respectively.
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| http://dx.doi.org/10.3390/molecules23020491 | DOI Listing |
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