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Fatal case of imported visceral leishmaniasis in a dog caused by Leishmania infantum in French Guiana.
Vet Parasitol Reg Stud Reports
October 2024
Laboratoire Tropical Biome and ImmunoPathophysiology (TBIP), Université de Guyane, Cayenne, French Guiana; Université de Lille, CNRS, Inserm, Institut Pasteur de Lille, Centre Hospitalier Régional Universitaire de Lille, U1019-UMR9017-CIIL Centre d'Infection et d'Immunité de Lille, 59000 Lille, France. Electronic address:
Article Synopsis
- - The report discusses a case of fatal canine visceral leishmaniasis (VL) in a 2-year-old pug from Brazil, which was imported to French Guiana, a region not typically associated with this disease.
- - The dog initially showed a skin issue that healed, but later developed serious symptoms, leading to suspicion of VL, which was confirmed posthumously by testing for L. infantum.
- - This case highlights the rarity of canine VL in French Guiana and suggests a need for increased local surveillance to monitor potential transmission routes of the parasite.
Chronic Prurigo.
J Dtsch Dermatol Ges
June 2024
Department of Dermatology and Competence Center for Chronic Pruritus (KCP), University Hospital Münster, Münster, Germany.
Article Synopsis
- * The main type of CPG is chronic nodular prurigo (CNPG), and recent advances in understanding its causes have led to new treatment options.
- * Dupilumab is the first treatment approved for moderate to severe CNPG, while several other promising therapies, including biologics and Janus kinase inhibitors, are currently undergoing clinical trials.
Wide-spread Pruriginous Lesions with Flagellate Scarring.
Dermatol Pract Concept
October 2023
Department of Dermatology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Chronic Prurigo Including Prurigo Nodularis: New Insights and Treatments.
Am J Clin Dermatol
January 2024
Department of Dermatology, Center for Chronic Pruritus, University Hospital Münster, Von-Esmarch-Str. 58, 48149, Münster, Germany.
Article Synopsis
- Chronic prurigo (CPG) is a painful skin condition characterized by intense itch lasting over six weeks, which leads to skin lesions and frequent scratching, significantly impacting patients' mental health and quality of life.
- Chronic prurigo of nodular type (CNPG) is the most common form of CPG and this review explores its clinical features, disease burden, and underlying mechanisms while highlighting current and emerging therapies.
- Dupilumab is the first approved systemic treatment for CNPG, with ongoing clinical trials investigating other promising therapies, including biologics and small molecules, aimed at improving patient care and understanding of the disease.
Zinc Oxide Patches Are a Highly Effective Treatment for Chronic Prurigo: A Randomized Split-Body Study.
Dermatology
December 2023
Department of Dermatology, University Hospital Zurich USZ, Zurich, Switzerland.
Background: Chronic prurigo (CPG) presents with pruriginous lesions and reduced quality of life (QoL). Established treatment options are often unsatisfying. Little is known about the efficacy of topical occlusive treatments.
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