Taurine (TA) ingestion has been touted as blunting the deleterious effects of ethanol (ET) ingestion on motor performance. This study investigated the effects of ingestion of 0.6 mL·kg of ET, 6 grams of TA, and ethanol in combination with taurine (ET+TA) on economy of movement (EM) and heart rate (HR). Nine volunteers, five female (22 ± 3 years) and four male (26 ± 5 years), participated in a study that used a counterbalanced experimental design. EM and HR were measured for 6 min while the subjects were pedalling at a fixed load 10% below the anaerobic threshold. The blood alcohol concentration (BAC) was similar between ET and ET+TA treatments at 30 min after ingestion and after exercise (12.3 mmol·L vs. 13.7 mmol·L, and 9.7 mmol • L vs 10.9 mmol·L, respectively). EM was significantly different among treatments, with lower mL·W following ingestion of TA (-7.1%, p<0.001) than placebo and ET+TA (-2.45%, p=0.001) compared to ET. HR (bpm) was significantly (p<0.05) higher for ET (137 ± 14 bpm) than the other three treatments (placebo = 129 ± 14 bpm; TA = 127 ± 11 bpm; TA+ET = 133 ± 12 and ET = 137 ± 14 bpm). Taurine improved EM when compared to placebo or ET, and reduced HR when compared to ET. The combination of ET+TA also enhanced EM compared to placebo, and reduced HR in comparison to ET alone. Therefore, these findings indicate that taurine improves EM and counteracts ethanol-induced increases in HR during submaximal exercise.
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http://dx.doi.org/10.5114/biolsport.2017.69823 | DOI Listing |
PLoS One
January 2025
Department of Electrical and Computer Engineering, University of Maryland, College Park, MD, United States of America.
Complex systems, such as in brains, markets, and societies, exhibit internal dynamics influenced by external factors. Disentangling delayed external effects from internal dynamics within these systems is often difficult. We propose using a Vector Autoregressive model with eXogenous input (VARX) to capture delayed interactions between internal and external variables.
View Article and Find Full Text PDFJMIR Infodemiology
January 2025
Computational Social Science DataLab, University Institute of Research for Sustainable Social Development (INDESS), University of Cadiz, Jerez de la Frontera, Spain.
Background: During the COVID-19 pandemic, social media platforms have been a venue for the exchange of messages, including those related to fake news. There are also accounts programmed to disseminate and amplify specific messages, which can affect individual decision-making and present new challenges for public health.
Objective: This study aimed to analyze how social bots use hashtags compared to human users on topics related to misinformation during the outbreak of the COVID-19 pandemic.
Alzheimers Dement
December 2024
Dokuz Eylul University Hospital Neurology Department, Izmir, Turkey.
Background: Early-onset Alzheimer's disease (EOAD), manifesting before age 65, demands nuanced diagnostic approaches. FDG18-PET unveils metabolic insights, the MRI scale captures structural changes, and ACE-R assesses cognitive impairment details. A holistic evaluation enhances diagnostic precision and enriches our understanding of cognitive decline in early-onset presentations.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Background: Fatigue is prevalent in later life and may increase dementia risk independent of health conditions. Yet, existing epidemiologic studies include samples that are not nationally representative of U.S.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Dokuz Eylul University Hospital Neurology Department, Izmir, Turkey.
Background: Early-onset Alzheimer's disease (EOAD), distinct from late-onset cases, tends to present with atypical cognitive decline, such as, progressive aphasia, apraxia, visuospatial and comportmental impairments,. This study aims to investigate correlations between clinical presentation and PET imaging findings in EOAD patients.
Method: A retrospective analysis was conducted on CSF confirmed EOAD patients.
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