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Automatic Detection of Cognitive Impairment in Patients With White Matter Hyperintensity Using Deep Learning and Radiomics.
Am J Alzheimers Dis Other Demen
March 2025
Pathology Department, Chongqing UniversityCentral Hospital, Chongqing Emergency Medical Center, Chongqing, China.
White matter hyperintensity (WMH) is associated with cognitive impairment. In this study, 79 patients with WMH from hospital 1 were randomly divided into a training set (62 patients) and an internal validation set (17 patients). In addition, 29 WMH patients from hospital 2 were used as an external validation set.
View Article and Find Full Text PDFHand function recovery after extended radial forearm free flap: A case series of a progressive therapy protocol.
J Hand Ther
March 2025
Department of Plastic Surgery, Vanderbilt University Medical Center, Nashville 37232, TN, USA. Electronic address:
Background: Restoration of hand function postextended radial forearm free flap (E-RFFF) is vital but challenging due to complex forearm anatomy and potential complications like reduced range of motion and sensory deficits. Traditional rehabilitation protocols often do not effectively address these issues.
Purpose: This study aims to explore the effectiveness of a hand therapy protocol that incorporates early active motion to enhance recovery outcomes after E-RFFF.
Dual-energy CT angiography-Guided vascularised free thoracodorsal artery lateral branch chimeric flaps for complex maxillofacial defect repair: An anatomical and clinical study.
J Craniomaxillofac Surg
March 2025
Department of Stomatology, Second Xiangya Hospital, Central South University, Changsha, China.
A modified thoracodorsal artery lateral branch (TDAL) chimeric flap was developed using dual-energy computed tomography (CT) angiography data of perforators to explore the anatomical characteristics and postoperative outcomes of TDAL flaps in complex maxillofacial defect repair. TDAL flaps were harvested from patients with locally advanced oral cancer. Preoperative perforator detection was performed with dual-energy CT angiography.
View Article and Find Full Text PDFThe role of flaps in preventing lower extremity amputations.
Semin Vasc Surg
March 2025
Department of Plastic and Reconstructive Surgery, Corewell Health East William Beaumont University Hospital, Royal Oak, Michigan, USA.
The increasing prevalence of chronic limb-threatening ischemia and diabetes mellitus has led to a surge in lower extremity amputations, driven by the combination of peripheral arterial disease and extensive wounds. Although revascularization often addresses ischemia, severe wounds pose a significant risk of amputation. Flaps, which involve the transfer of vascularized tissue, can provide immediate closure of complex wounds, particularly those involving bone or tendon exposure, where skin grafts are insufficient.
View Article and Find Full Text PDFPercutaneous approach to deep vein arterialization for the "no-option" chronic limb-threatening ischemia patient.
Semin Vasc Surg
March 2025
University of Pennsylvania, Penn Medicine, 3400 Civic Center Boulevard, PCAM 14 South, Philadelphia, PA 19104. Electronic address:
Chronic limb-threatening ischemia is an advanced stage of peripheral artery disease characterized by rest pain or tissue loss. Treatment of patients classified as ``no-option'' CLTI remains particularly challenging, as historically their primary treatment has been limited to major amputation. Venous arterialization has emerged as a promising alternative in this difficult-to-treat population.
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