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Above-Knee Amputation in a 69-Year-Old Male with Gouty Tophi Complicated by Necrotizing Fasciitis - A Case Report.
Mod Rheumatol Case Rep
December 2024
Department of Plastic and Reconstructive Surgery, Saint Paul Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Gout is the most prevalent form of inflammatory arthritis in males as a result of high uric acid levels that cause deposition of monosodium urate crystals in soft tissues, bones and joints. It commonly presents as swollen, erythematous and painful joint. Necrotizing fasciitis is rapidly progressing aggressive soft tissue infection that spreads along the fascial planes sparing the skin; it is very uncommon for necrotizing fasciitis to occur as a complication of gouty arthritis.
View Article and Find Full Text PDFDiabetic Charcot neuroarthropathy: A threat to both limb and life.
Diabetes Obes Metab
January 2025
Midstate Endocrine Associates, Lipscomb University, Nashville, Tennessee, USA.
Article Synopsis
- Diabetic Charcot neuroarthropathy (DCN) is a rare but serious complication of diabetes, particularly affecting those with diabetic neuropathy, where the incidence rises to 30%, especially among type 1 diabetics.
- It typically presents as a painless, swollen, and warm foot or ankle, with MRI and X-ray revealing specific joint abnormalities, often in a particular order.
- Treatment primarily involves prolonged immobilization and offloading, with potential but unproven therapeutic options; there's a high risk of amputation and increased mortality, especially when foot ulcers are present, necessitating surgical intervention to prevent recurrence.
Forefoot inflammation in recent-onset ACPA-positive and ACPA-negative RA: clinically similar, but different in underlying inflamed tissues.
RMD Open
October 2024
Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.
Article Synopsis
- * ACPA-negative patients generally have more swollen joints, but the prevalence of swollen metatarsophalangeal (MTP) joints and walking disabilities is similar across both groups, while ACPA-positive patients show greater prevalence of inflamed tissues.
- * Different types of inflammation are associated with specific symptoms: in ACPA-positive patients, intermetatarsal bursitis relates to MTP joint issues, while in ACPA-negative patients, synovitis is more
Pestalotiopsis, a rare cause of mycetoma; A case report.
Indian J Med Microbiol
September 2024
Dept. of Microbiology, All India Institute of Medical Sciences, Raipur, INDIA. Electronic address:
Article Synopsis
- Pestalotiopsis is a plant pathogen that rarely causes human infections, but a case in India marks its first identification from a mycetoma patient.
- A 66-year-old male farmer showed symptoms of a swollen foot and multiple discharging sinuses after a twig prick injury.
- Laboratory findings included fragmented fungal elements and characteristic white to pale honey-colored colonies, and the patient was successfully treated with systemic Itraconazole.
Gout arthritis of the ankle successfully treated with arthroscopic debridement: A case report.
Int J Surg Case Rep
September 2024
Department of Orthopaedic and Traumatology, Dr.Cipto Mangunkusumo Hospital, Faculty of Medicine Universitas Indonesia, Indonesia. Electronic address:
Article Synopsis
- Gout is an inflammatory arthritis caused by the accumulation of uric acid crystals, mainly affecting joints like the big toe and ankle, and treatment focuses on reducing uric acid levels and managing pain.
- A 32-year-old male with hyperuricemia had a painful swollen ankle; MRI showed a ligament issue, leading to an arthroscopic surgery that diagnosed gout and removed crystal deposits, resulting in significant improvement.
- Gout can mimic other joint injuries, making diagnosis tricky; successful arthroscopic treatment requires expert planning and careful removal of crystals to avoid complications.
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