An optical trap for storing femtosecond laser pulses to enhance the interaction effectiveness with optically thin targets is being proposed and investigated. Presently, we studied the trapping of 10-200 fs laser pulses of wavelength 800 nm, 1 μJ energy per pulse, and 10 Hz repetition rate. To compensate the optical losses in the trap, a Ti: Sapphire crystal as an amplifying medium is being considered, which should be synchronously pumped by the second harmonic of the Nd: YAG laser. Due to the propagation of the short pulses through optical trap components, group velocity dispersion introduces a significant broadening in pulse duration. To compensate for this broadening, a chirped mirror with suitable parameters is being proposed. An increase of the average power of the laser pulse in the optical trap that includes an amplifying medium (Ti: Sapphire crystal) by a factor of 805 compared to a single passage of the laser pulse was derived. It should be possible to store the laser pulse in the optical trap for >4 μs with constant power and with a repetition rate of up to 250 MHz.
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http://dx.doi.org/10.1364/AO.57.001212 | DOI Listing |
ACS Appl Mater Interfaces
January 2025
School of Materials Science and Engineering, Tianjin Key Lab for Rare Earth Materials and Applications, Nankai University, Tianjin 300350, China.
For silicon-based devices using dielectric oxides doped with rare earth ions, their electroluminescence (EL) performance relies on the sufficient carrier injection. In this work, the atomic GaO layers are inserted within the Er-doped GeO nanofilms fabricated by atomic layer deposition (ALD). Both Ga(CH) and Ga(CH) could realize the ALD growth of GaO onto the as-deposited GeO nanofilm with unaffected deposition rates.
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January 2025
Department of Chemical Engineering, University of Massachusetts Amherst, Amherst, MA, 01003, USA.
X-ray crystallography is one of the leading tools to analyze the 3-D structure, and therefore, function of proteins and other biological macromolecules. Traditional methods of mounting individual crystals for X-ray diffraction analysis can be tedious and result in damage to fragile protein crystals. Furthermore, the advent of multi-crystal and serial crystallography methods explicitly require the mounting of larger numbers of crystals.
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December 2024
Laboratory of Immunobiology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
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December 2024
Centro de Biología Molecular "Severo Ochoa" (CSIC-UAM), and Department of Molecular Biology, Universidad Autónoma de Madrid, Madrid, Spain.
Structural biology techniques have greatly contributed to unveiling the interplay between molecular structure, physico-chemical properties, and biological function of viruses. In recent years, classic structural approaches are being complemented by single-molecule techniques such as atomic force microscopy and optical tweezers to study physical features of viral particles that are not accessible to classic structural techniques. Among these features are mechanical properties such as stiffness, intrinsic elasticity, tensile strength, and material fatigue.
View Article and Find Full Text PDFSubcell Biochem
December 2024
Centro de Tecnologías Físicas, Universitat Politècnica de València, Valencia, Spain.
A virus is a complex molecular machine that propagates by channeling its genetic information from cell to cell. Unlike macroscopic engines, it operates in a nanoscopic world under continuous thermal agitation. Viruses have developed efficient passive and active strategies to pack and release nucleic acids.
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