Objective: To discuss the clinical features of cerebral schistosomiasis.
Methods: The clinical data of fourteen patients with cerebral schistosomiasis from March 2010 to March 2016 were collected and analyzed retrospectively.
Results: The schistosomiasis immunological tests of sera and cerebrospinal fluids from the fourteen patients were all positive. Eosinophils increased in ten cases, and the proportion was 5.1%-60.3%. Schistosoma eggs were found in seven cases by the fecal Kato-Katz method. Fourteen cases were all infected with . Twelve cases were diagnosed as chronic type, and two cases as acute type. Thirteen patients received medical treatment, of which twelve were cured, and one improved. One patient received the surgical resection of the lesion.
Conclusions: The clinical manifestations of cerebral schistosomiasis mainly include seizure, headache, dizziness and fever. In the enhanced head magnetic resonance imaging (MRI), the lesions are clustered and merged into lumps, which is the characteristic image of cerebral schistosomiasis japonica. The praziquantel treatment can achieve a good prognosis.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.16250/j.32.1374.2017062 | DOI Listing |
Front Immunol
December 2024
Department of Critical Care Medicine, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Introduction: Cerebral schistosomiasis is a rare but severe manifestation of infection, often leading to significant neurological impairment. This case report details the clinical presentation, diagnostic challenges, and treatment of a 3-year-old girl with cerebral schistosomiasis in Sichuan, China.
Case Description: A 3-year-old girl from a rural area in Sichuan, China, presented with a 3-month history of unstable walking, left facial paralysis, drowsiness, and intermittent fever.
Eur J Case Rep Intern Med
October 2024
Department of Internal Medicine, Hamad Medical Corporation, Doha, Qatar.
Unlabelled: Neuroschistosomiasis, a rare manifestation of schistosomiasis affecting the central nervous system (CNS), can result in severe neurological complications if not promptly diagnosed and treated. The condition arises due to the development of granulomas around eggs that become lodged within the CNS. Here we present a case report involving a young Filipino individual who had recurrent, uncontrolled seizures, ultimately attributed to neuroschistosomiasis.
View Article and Find Full Text PDFNat Immunol
November 2024
Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Skin uses interdependent cellular networks for barrier integrity and host immunity, but most underlying mechanisms remain obscure. Herein, we demonstrate that the human parasitic helminth Schistosoma mansoni inhibited pruritus evoked by itch-sensing afferents bearing the Mas-related G-protein-coupled receptor A3 (MrgprA3) in mice. MrgprA3 neurons controlled interleukin (IL)-17 γδ T cell expansion, epidermal hyperplasia and host resistance against S.
View Article and Find Full Text PDFJ Neuroimmune Pharmacol
July 2024
Zoology and Entomology Department, Faculty of Science, Helwan University, Cairo, Egypt.
Recombinant interleukin-22 (rIL-22) has been reported as a protective agent in murine models of diseases driven by epithelial injury. Parasites have a circadian rhythm and their sensitivity to a certain drug may vary during the day. Therefore, this work aimed to investigate the effect of rIL-22 administration at different times of the day on the inflammation, oxidative status, and neurotransmitter release in the gut-brain axis of the Schistosoma mansoni-infected mice.
View Article and Find Full Text PDFParasit Vectors
May 2024
National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (National Center for Tropical Diseases Research); Key Laboratory of Parasite and Vector Biology, National Health Commission; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases; WHO Collaborating Centre for Tropical Diseases, National Center for International Research On Tropical Diseases, Shanghai, People's Republic of China.
Background: Angiostrongyliasis is a highly dangerous infectious disease. Angiostrongylus cantonensis larvae migrate to the mouse brain and cause symptoms, such as brain swelling and bleeding. Noncoding RNAs (ncRNAs) are novel targets for the control of parasitic infections.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!