[Assessment of Vascular Stiffness in Normotensive Patients With Familial Hypercholesterolemia].

Aim: to analyze parameters of vascular stiffness and augmentation index in patients with familial hypercholesterolemia (FH).

Materials And Methods: We compared parameters of vascular stiffness of 88 normotensive FH patients (mean age 41.95±1.43 years, 43 men [48.9 %]) and 68 subjects with normal blood lipid spectrum (mean age 37.58±1.02 years, 21 men [30.9 %]). FH was diagnosed according to the criteria of the Dutch Lipid Clinic Network. Examination included lipid profile, 24‑hour blood pressure (BP) monitoring with assessment of arterial stiffness.

Results: Normotensive FH patients had higher pulse wave velocity (PWV) (7.99±0.17 m/s) in comparison with patients with normal lipid spectrum (6.87±0.10 m/s), p.