The H+-ATPase activity of mitochondria from the rat brain, liver heart and skeletal muscles was studied as affected by 1 at. of oxygen pressure (60 min), 5 at. (10 min) and 5 at. up to the convulsive and terminal states. The effect of 1 at. of oxygen pressure for 60 min and 5 at. for 10 min. causes an increase in the H+-ATPase activity of mitochondria of the investigated tissues. But under convulsive and terminal stages of 5 at. hyperbaric oxygenation the activity of H+-ATPase decreases, and to the greatest extent in the brain mitochondria.

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