From December 1981 to April 1984, 56 dialysed patients have been enrolled in a sero-vaccination program in which injections of Hevac B vaccine and anti-HBs immunoglobulin have been repeated to obtain anti-HBs response. Anti-HBs antibodies were distinguished from passively transmitted anti-HBs whenever anti-HBs levels above 33 mUI/ml were found 60 days after the last injection of hepatitis B immune globulins (4 ml). Among 39 patients (25 men, 14 women) (mean age 59 years) the proportion of vaccine responders was 44%, 67%, 82%, 90% after respectively 4, 6, 10, 14 injections of Hevac B vaccine. Age, male sex and duration of dialysis were found to decrease the immune response to the vaccine. Multiple injections and maintenance of protective anti-HBs (titer greater than 20 mUI/ml) can be considered as the most effective method to eradicate HBV infection from dialysis centers.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Impact of nutritional status and pulmonary function on short- and long-term overall survival in hemodialysis patients.
PLoS One
January 2025
Department of Pulmonary Diseases, Uludag University Faculty of Medicine, Bursa, Turkey.
Background: End-stage renal disease (ESRD) patients frequently experience protein-energy wasting (PEW), which increases their morbidity and mortality rates.
Objective: This study explores the effects of nutritional status and pulmonary function on the short- and long-term mortality of ESRD patients undergoing hemodialysis.
Materials And Methods: 67 consecutive ESRD patients on maintenance hemodialysis were included in the study.
Supporting equitable access to kidney transplant in remote Western Australia using continuous quality improvement.
Int J Qual Health Care
January 2025
Kimberley Renal Services, PO Box 1377, Broome, Western Australia 6725, Australia.
Background: Despite an epidemic of end-stage kidney disease in the Australian Aboriginal and Torres Strait Islander population, disparities in access to kidney transplantation persist. The journey to a successful kidney transplant is long, with an initial suitability assessment required before waitlist-specific activities begin. In an Aboriginal Community Controlled renal service, we aimed to: (i) design and implement a continuous quality improvement (CQI) approach to transplant suitability assessment, (ii) provide transplant suitability assessments for all patients of the service, (iii) describe what temporary contraindications to kidney transplantation should be the focus of health service improvements, (iv) explore participant experiences with the suitability assessment process, and (v) use our findings to inform pre- and post-transplant model of care development within Kimberley Renal Services.
View Article and Find Full Text PDFProperties of Uremic Solutes That Allow Their Effective Control by Hemodialysis.
Kidney360
January 2025
Departments of Medicine, Stanford University and VA Palo Alto HCS, Palo Alto CA USA.
Background: If the GFR falls far enough, uremic symptoms such as anorexia and nausea prompt the initiation of dialysis. Thrice weekly hemodialysis can prevent recurrence of these symptoms even when patients become anuric. To accomplish this it must maintain the plasma levels of the uremic solutes which cause these symptoms lower than they were when dialysis was initiated.
View Article and Find Full Text PDFKidney Replacement Therapies and Outcomes in Children With Crush Syndrome-Associated Kidney Injury.
JAMA Netw Open
January 2025
Department of Pediatric Intensive Care Medicine, Life Support Center, Hacettepe University, Ankara, Turkey.
Importance: This study addresses the characteristics, kidney replacement therapy (KRT) modalities, and outcomes in children diagnosed with crush syndrome following an earthquake in Turkey.
Objective: To analyze the associations of different KRT modalities with long-term dialysis dependency and length of stay (LOS) in the pediatric intensive care unit (PICU).
Design, Setting, And Participants: This multicenter, prospective, and retrospective cohort study was conducted across 20 PICUs in Turkey.
A period prevalence study of palliative care need and provision in adult patients attending hospital-based dialysis units.
J Nephrol
January 2025
School of Nursing, Curtin University, Kent Street, Bentley, WA, 6102, Australia.
Background: Advanced chronic kidney disease is a life-limiting disease that is known to benefit from palliative care. Unmet palliative care need in patients with kidney failure is commonly reported but the level of need among patients receiving haemodialysis is unknown.
Methods: A period prevalence study of adult patients attending two hospital-based dialysis units was conducted.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!