Purpose: In this study we report an uncommon endoscopic endonasal image of an atrophic optic nerve as seen after surgical removal of a suprasellar meningioma. The peculiarity of this case is the long-lasting underestimated ocular symptomatology of the patient who reported a 15-year history of impairment of vision on her left eye.
Methods: A 51-year-old woman was admitted to our hospital complaining of a 15-year history of impairment of vision on her left eye. After making serendipitously the diagnosis of a suprasellar mass, we performed endoscopic endonasal surgery.
Results: The tumor was reached from below and removed safely, without manipulation of the optic pathways. At the end of tumor removal, the impressive left optic nerve atrophy due to enduring local tumor compression was visualized.
Conclusions: To the best of our knowledge, no endoscopic endonasal image with such features has been provided in the pertinent literature. Possibly, this contribution will help identify damaged optic nerves during endoscopic endonasal surgery.
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http://dx.doi.org/10.1016/j.wneu.2018.02.032 | DOI Listing |
Cureus
December 2024
Neurological Surgery, Loyola University Medical Center, Maywood, USA.
Introduction Surgical resection remains a standard treatment of non-functioning pituitary adenomas (NFPA). These tumors have significant intratumoral variability of growth rates and texture hardness. This preliminary study aims to identify variations in gene expression of different locations and textures within the same tumor to better explain tumor pathophysiology.
View Article and Find Full Text PDFJ Surg Case Rep
January 2025
Department of Otolaryngology-Head and Neck Surgery, King Fahad Specialist Hospital, Dammam 32253, Saudi Arabia.
Isolated sphenoid sinus disease (ISSD) is a rare condition that accounts for roughly 3% of all sinusitis cases. ISSD is predominantly caused by infectious and inflammation processes, with underlying fungal pathologies. This case series aims to illustrate the endonasal endoscopic management of different isolated sphenoid fungal pathologies.
View Article and Find Full Text PDFWorld Neurosurg
January 2025
Department of Neurosurgery, Emory University, Atlanta, Georgia, USA; Department of Otolaryngology, Emory University, Atlanta, Georgia, USA. Electronic address:
Background: Giant pituitary neuroendocrine tumor (GPitNET) are challenging tumors with low rates of gross total resection (GTR) and high morbidity. Previously reported machine-learning (ML) models for prediction of pituitary neuroendocrine tumor extent of resection (EOR) using preoperative imaging included a heterogenous dataset of functional and non-functional pituitary neuroendocrine tumors of various sizes leading to variability in results.
Objective: The aim of this pilot study is to construct a ML model based on the multi-dimensional geometry of tumor to accurately predict the EOR of non-functioning GPitNET.
Endocr Metab Immune Disord Drug Targets
January 2025
Department of Neurosurgery, Istanbul University-Cerrahpaşa, Istanbul, Turkey.
Background: Primary pituitary abscess is a rare disease with no specific symptoms for pituitary abscess alone. A preoperative diagnosis is quite challenging due to unclear imaging findings.
Case Presentation: We report the case of a patient with a pituitary lesion who presented with hypopituitarism, diabetes insipidus, and visual field defect and was misdiagnosed as a possible cystic pituitary adenoma.
Sci Rep
January 2025
Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.
Currently, the direct endonasal approach is widely used in endoscopic endonasal surgery (EES) for pituitary neuroendocrine tumor. However, a large posterior septal perforation is inevitable. We routinely utilize a modified para/transseptal approach using the combination of a Killian and a contralateral rescue flap incision (PTSA with K-R incision).
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