AI Article Synopsis
- The study focused on isolating and analyzing quinazoline alkaloids from the unripe fruit of Evodia rutaecarpa, highlighting their diverse biological functions.
- Three new alkaloids, evodiamide A, B, and C, were discovered along with eight previously known quinazolines in the methanol extract.
- The compound rhetsinine was particularly noted for its strong pesticide potential, showing effective inhibition against several harmful bacteria with specific EC values.
Article Abstract
In this research, we investigated the profile and bioactivities of quinazoline alkaloids, a class of natural products boasting multiple bioactivities, from the unripe fruit of Evodia rutaecarpa (Juss.) Benth. Three new quinazoline alkaloids, evodiamide A (1), evodiamide B (2), and evodiamide C (3), as well as eight known quinazolines, were isolated from the MeOH extract of E. rutaecarpa. The new compounds are rare quinazolinedione derivatives with linked heterocyclic nuclei. Among these quinazolines, rhetsinine (8) showed potential as a pesticide and exhibited excellent inhibition against Xanthomonas oryzae pv. oryzae, Xanthomonas oryzae pv. oryzicola, and Xanthomonas campestris pv. campestris, with respective EC values of 3.13, 14.32, and 32.72 nmol.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.fitote.2018.02.003 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!