This study examines melanocyte density counts in imiquimod-treated lentigo maligna and negative control biopsy specimens to determine if there was a measurable difference in melanocyte density.
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http://dx.doi.org/10.1001/jamadermatol.2017.5632 | DOI Listing |
Vet Dermatol
January 2025
Department of Veterinary Medicine, University of Perugia, Perugia, Italy.
Background: In humans, the presence of an even distribution of melanocytes within the epidermal basal layer allows for uniform pigmentation in healthy and young individuals. Moreover, despite high variability in skin colours and tones, interindividual melanocyte density variability is low. However, dogs display a high intraindividual pigmentary variability in different anatomical areas.
View Article and Find Full Text PDFMicrosc Res Tech
December 2024
Zoology and Entomology Department, Faculty of Science, Assiut University, Assiut, Egypt.
This study aimed to describe the morphological features and microstructure of the upper, lower, and third eyelids of the black-winged kite, Elanus caeruleus, and to characterize the organized lymphoid follicles and lymphocytes in the eyelid mucosa. Additionally, it aimed to illustrate the importance of the eye adnexa in the eye's immune protection. The upper, lower, and third eyelids display varying morphological differences that seem to be closely linked to the birds' way of life, indicating adjustments to their environment and eating behaviors.
View Article and Find Full Text PDFBiochim Biophys Acta Rev Cancer
December 2024
Department of Plastic Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, China. Electronic address:
Melanoma is a highly invasive malignant tumor originating from melanocytes, with increasing incidence in recent years. Ferroptosis is an iron-dependent and non-apoptotic form of programmed cell death characterized by the accumulation of lipid peroxides and reactive oxygen species. Morphologically, ferroptosis exhibits the alteration in cells, such as reduced mitochondrial volume, increased density of bilayer membrane, and a decrease or disappearance of mitochondrial cristae.
View Article and Find Full Text PDFOcul Immunol Inflamm
December 2024
Sakarya University Education and Research Hospital, Department of Ophthalmology, Sakarya, Turkey.
Purpose: This study aimed to the detect of structural and functional changes in the retina and choroid in patients with vitiligo using optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA).
Materials And Methods: Thirty patients with vitiligo and 30 healthy participants were enrolled in the study. Central macular thickness (CMT), retina nerve fiber layer (RNFL) thickness, choroidal thickness (CT), foveal avascular zone (FAZ) area, and superficial and deep vascular density (VD) ratios were compared between the groups.
Microsc Res Tech
November 2024
Faculty of Veterinary Medicine, Department of Anatomy and Embryology, Damanhour University, Damanhour, Egypt.
The red-eared slider turtle, a species facing environmental challenges and habitat loss, exhibits a complex skin architecture that is crucial for its adaptation and survival. Our study aims to provide a comprehensive characterization of the turtle's skin structure and to elucidate the distribution and localization of its various cellular components, with a focus on understanding the skin's role in adaptation and ecological interactions. To achieve these goals, we employed light microscopy, transmission electron microscopy (TEM), and comprehensive immunofluorescence using 10 specific antibodies.
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