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A Novel Report of Müllerian (Vaginal/Uterine) Agenesis in a Newborn Girl With LUMBAR Syndrome.
Pediatr Dermatol
January 2025
Division of Dermatology, Children's Mercy Kansas City, Kansas City, Missouri, USA.
LUMBAR syndrome is characterized by lower body segmental infantile hemangiomas, urogenital abnormalities/hemangioma ulceration, spinal cord malformations, bony deformities, anorectal malformations/arterial anomalies, and/or renal anomalies. Here we present an infant girl with LUMBAR syndrome who was also discovered to have Müllerian agenesis, defined as absent uterus or nonfunctional uterine remnants. While vaginal and uterine duplications are included among the diagnostic criteria for LUMBAR syndrome, this is the first case of associated Mullerian agenesis.
View Article and Find Full Text PDFAccessory Cavitated Uterine Malformation (ACUM): An Underdiagnosed, Treatable Cause of Dysmenorrhea.
Cureus
December 2024
Department of Obstetrics and Gynaecology, Tata Main Hospital, Jamshedpur, IND.
An uncommon and recently identified Müllerian anomaly is the accessory cavitated uterine mass (ACUM). It is distinguished by the presence of a noncommunicating auxiliary cavity inside the uterus, located near and surrounded by uterine smooth muscle, and bordered by functioning endometrium beneath the round ligament's insertion, with a perfectly healthy uterus, ovaries, tubes, and cavity. Given that it is a congenital ailment with a persistent Müllerian duct at the level of the round ligament, primarily resulting from gubernaculum dysfunction, it usually manifests clinically as childhood dysmenorrhea in girls.
View Article and Find Full Text PDFComplex Presentation of Uterus Didelphys With Bilateral Leiomyomas: A Case Report.
Case Rep Obstet Gynecol
January 2025
Department of Medicine, Ethio Tebib Hospital, Addis Ababa, Ethiopia.
Müllerian duct anomalies and uterine leiomyomas represent distinctive facets of female reproductive health. While uterine leiomyomas are prevalent reproductive pathologies, the coexistence of Müllerian anomalies and leiomyomas is relatively uncommon. This case study examines the complex medical and surgical management of a woman who initially presented with chronic abdominal pain and swelling.
View Article and Find Full Text PDFAnti-Müllerian hormone regulates ovarian granulosa cell growth in PCOS rats through SMAD4.
Int J Gynaecol Obstet
January 2025
Center for Reproductive Medicine, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, China.
Objective: Polycystic ovary syndrome (PCOS) is a diverse condition with an unknown cause. The precise mechanism underlying ovulatory abnormalities in PCOS remains unclear. It is widely believed that malfunction of granulosa cells is the primary factor contributing to aberrant follicular formation in PCOS.
View Article and Find Full Text PDFIncidental finding of didelphys uterus with twin pregnancy in each cavity; A rare case report.
Int J Surg Case Rep
January 2025
Addis Ababa University, College of Health Sciences, Department of Internal Medicine, Addis Ababa, Ethiopia.
Introduction And Importance: Uterine didelphys is a Müllerian duct anomaly with two uteri and cervices, with or without a vaginal septum. A di-cavitary twin pregnancy in a uterus didelphys is an infrequent occurrence.
Case Presentation: A 27-year-old woman, gravida 3, para 2, at a gestational age of 37 weeks and 4 days, presented with pushing-down pain.
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