Less Is Best in the Convergent Evolution of Typhoidal Salmonella.

Cell Host Microbe

Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO 80045, USA; Veterans Affairs Eastern Colorado Health Care System, Denver, CO 80220, USA. Electronic address:

Published: February 2018

Related works in this issue of Cell Host & Microbe (Bronner et al., 2018) and in a recent issue of Cell Reports (Hiyoshi et al., 2018) demonstrate how loss-of-function mutations in butyrate utilization and lipopolysaccharide O-antigen processing contribute to evasion of innate host defenses and the convergent evolution of distinct typhoidal Salmonella lineages.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978414PMC
http://dx.doi.org/10.1016/j.chom.2018.01.009DOI Listing

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