AI Article Synopsis

  • An agarose gel matrix was used to culture chondrocytes from human donors of different ages.
  • These chondrocytes produced a pericellular matrix, synthesized collagen type II, and glyco-saminoglycans, mimicking the distribution found in articular cartilage.
  • The electron microscopy results showed that the cultured chondrocytes closely resembled those found in actual cartilage tissue.

Article Abstract

An agarose gel matrix was utilized to grow chondrocytes from human donors of various ages in cell culture. The chondrocytes produced the pericellular matrix characteristic for such cells and synthesized collagen type II as well as glyco-saminoglycans. The latter exhibit the typical distribution pattern of the respective articular cartilage matrix. The electron-microscopic appearance of the cultured chondrocytes closely resembles that of chondrocytes in sections of the original cartilage.

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Source
http://dx.doi.org/10.3109/03008208609167140DOI Listing

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