Purpose: The buy-and-bill model of pharmaceuticals has been an economic reality for medical oncology practices for more than 30 years. Infusion services, once just a supportive service, grew exponentially in most practices between 1991 and 2000, to the point at which revenue from these services created a high, which made all things possible, including care of underinsured or uninsured patients. This altered state was further enhanced in the early part of this past decade when the introduction of high-cost chemotherapeutics and biologic agents created the euphoria of big business and a true dollar distortion for even the smallest oncology practice.
Results: In 2005, government and payer intervention forced average wholesale price to average sales price conversion to reduce the drug effect. Concurrently, payer scrutiny of utilization and medical necessity with further dose reductions, equating to margins, led many practices to experience painful drug withdrawal symptoms. Despite the enormous financial risk for unreimbursed expense and acknowledged spiraling decline of drug margins of greater than 30% since 2002, the seductive possibility of a financial fix keeps the practices hooked.
Conclusion: Many practices will make poor financial choices and will gamble with their financial health by consuming precious resources to support the habit. We propose the drug test: Run your practice financials without drugs. Can you cover the total practice expense without drugs? If not, determine your level of dependency on the drug margin, and adjust your service lines and salaries accordingly. We issue the following warning: Drug dependencies may be hazardous to the financial health of your organization.
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http://dx.doi.org/10.1200/JOP.2011.000441 | DOI Listing |
Pol J Vet Sci
June 2024
Department of Physiology, University of Veterinary and Animal Sciences, Syed Abdul Qadir Jilani (Out Fall) Road, Lahore 54000, Pakistan.
The present study was designed to evaluate the protective efficacy of troxerutin against cypermethrin-induced behavioral defects, motor function abnormalities, and oxidative stress in mice. Twenty-four adult female albino mice were randomly divided into four equal groups. The first group served as control, the second group was treated with cypermethrin (20 mg/kg b.
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June 2024
Department of Surgery, Faculty of Veterinary Medicine, University of Siirt, Kezer Campus, Veysel Karani District, University Street, Siirt/Türkiye.
In this study, a total of 32 Trueperella pyogenes strains isolated from different disease specimens in cattle, sheep and goats were examined. Antimicrobial susceptibility of the isolates to 10 antimicrobials were determined using the E-test method and MIC values of the antimicrobials were investigated. The genes that play a role in the antimicrobial resistance or virulence of T.
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December 2024
Department of Basic sciences, Faculty of Veterinary Medicine, Tabriz medical sciences branch, Islamic Azad University, 5159115705, Tabriz, Iran.
Male fertility is adversely influenced by diabetes. The beneficial effects of antioxidant bioflavonoids in improving fertility have been reported. This study was conducted to evaluate the effects of silymarin on diabetes mellitus-induced male reproductive impairment in rats by investigating its role in Hsp70 and Hsp90 expression.
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December 2024
Technology and Research Research & Development Center (MARGEM), Hatay Mustafa Kemal University, Hatay, Turkey.
Nicotine, the main toxic component of tobacco, directly or indirectly causes adverse effects on the liver metabolism. Melatonin, secreted by the pineal gland, has anti-apoptotic activity as well as antioxidant activity. The aim of this study was to reveal the antiapoptotic effects of melatonin in rats with experimentally induced chronic liver damage with nicotine.
View Article and Find Full Text PDFFront Biosci (Elite Ed)
November 2024
Department of Life Sciences, GITAM School of Science, Gandhi Institute of Technology and Management, 530045 Visakhapatnam, Andhra Pradesh, India.
Background: Amalgamation of metal-tolerant plant growth promoting rhizobacteria (PGPR) with biochar is a promising direction for the development of chemical-free biofertilizers that can mitigate environmental risks, enhance crop productivity and their biological value. The main objective of the work includes the evaluation of the influence of prepared bacterial biofertilizer (BF) on biometric growth parameters as well as physiological and biochemical characteristics of rapeseed ( L.) at copper action.
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