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Effects of supplementation of macular pigment carotenoids on ocular health: a Raman spectroscopic study of human blood serum of glaucoma patients.
Analyst
January 2025
Physical to Life Sciences Research Hub, Technological University Dublin, City Campus, Aungier Street, Dublin 2, D02 HW71, Ireland.
Carotenoids are known for their antioxidant and vision protection roles, with dietary supplements often promoted for eye health. An initial trial, the European Nutrition in Glaucoma Management (ENIGMA), assessed macular pigment optical density (MPOD) and other ocular parameters before and after supplementing glaucoma patients with macular pigment (MP) carotenoids. The trial confirmed significant improvements in clinical ocular health.
View Article and Find Full Text PDFA Pilot Study of the Gut Microbiota in Spine Fusion Surgery Patients.
HSS J
February 2025
Hospital for Special Surgery, New York, NY, USA.
Background: The microbiome has been identified as a contributor to bone quality. As skeletal health is critical to success of orthopedic surgery, the gut microbiome may be a modifiable factor associated with postoperative outcomes. For spine fusion surgery in particular, bone formation and sufficient bone mineral density are essential for successful outcomes.
View Article and Find Full Text PDFBone imaging modality precision and agreement between DXA, pQCT, and HR-pQCT.
JBMR Plus
February 2025
Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC 3168, Australia.
Quantifying precision error for DXA, peripheral QCT (pQCT), and HR-pQCT is crucial for monitoring longitudinal changes in body composition and musculoskeletal outcomes. Agreement and associations between bone variables assessed using pQCT and second-generation HR-pQCT are unclear. This study aimed to determine the precision of, and agreement and associations between, bone variables assessed via DXA, pQCT, and second-generation HR-pQCT.
View Article and Find Full Text PDFFine-root and leaf acquisitive traits decoupled from chloride accumulation in reflecting the differential salinity tolerance among hybrids.
Front Plant Sci
January 2025
CSIRO, Glen Osmond, Adelaide, SA, Australia.
Improving crop salinity management requires enhanced understanding of salinity responses of leaf and fine-root traits governing resource acquisition, ideally in relation to ion accumulation at intra- or inter-specific levels. We hypothesized that these responses are coupled towards integrated resource conservation for plants under prolonged salt treatment. We tested the hypothesis with a glasshouse experiment on saplings of six contrasting hybrids, subjected to either control or salt treatment (reverse osmosis water versus 3.
View Article and Find Full Text PDFChemopreventive Effects of Piper betle (Sirih) on High-Fat Diet-Induced and Azoxymethane-Induced Colon Cancer in Male Sprague-Dawley Rats.
Cureus
December 2024
Department of Biochemistry, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, MYS.
A high-fat diet could lead to obesity, increasing colorectal cancer risk due to dyslipidemia and chronic inflammation, while Piper betle (PB) exhibits anti-tumor, anti-inflammation, and anti-oxidant benefits. This study aimed to determine whether PB possesses chemopreventive effects on high-fat diet (HFD)-induced and azoxymethane (AOM)-induced colon cancer. Male Sprague-Dawley rats receiving either a normal diet or HFD were divided into control, PB, AOM, and AOM+PB subgroups which were then sacrificed after 24 weeks.
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