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Dementia Care Research and Psychosocial Factors.
Alzheimers Dement
December 2024
Massachusetts General Hospital, Boston, MA, USA.
Background: Underdiagnosis of Alzheimer's disease and related dementias (ADRD) leads to lost opportunities for timely intervention, increased healthcare costs, and underestimation of the true burden of disease. To address this problem, we developed an AI algorithm, Decipher-AI (DEtection of Cognitive Impairment PHenotypes in EHR), to screen primary care patients for undiagnosed cognitive impairment (CI). We evaluated performance across sociodemographic groups using 3 years of EHR data before the first diagnosis or most recent visit.
View Article and Find Full Text PDFTechnology and Dementia Preconference.
Alzheimers Dement
December 2024
Tilburg University, Tilburg, Netherlands.
Background: Developing culture-fair tests that measure constructs equivalently across different ethno-lingual groups is challenging, given the diverse cultural variations that impact neurocognitive measurement. Multi-level measurement invariance must be established before interpreting scores similarly across groups, both within and between cultures for meaningful comparisons.
Method: We set out to test whether a neurocognitive tool (BENCI) behaves the same way across the males (n = 311) and the females group (n = 291) using measurement invariance testing with multigroup confirmatory factor analysis.
Technology and Dementia Preconference.
Alzheimers Dement
December 2024
Massachusetts General Hospital, Boston, MA, USA.
Background: Underdiagnosis of Alzheimer's disease and related dementias (ADRD) leads to lost opportunities for timely intervention, increased healthcare costs, and underestimation of the true burden of disease. To address this problem, we developed an AI algorithm, Decipher-AI (DEtection of Cognitive Impairment PHenotypes in EHR), to screen primary care patients for undiagnosed cognitive impairment (CI). We evaluated performance across sociodemographic groups using 3 years of EHR data before the first diagnosis or most recent visit.
View Article and Find Full Text PDFSubgroups of cognitive impairments in schizophrenia characterized by executive function and their morphological features: a latent profile analysis study.
BMC Med
January 2025
Department of Psychiatry, National Clinical Research Center for Mental Disorders, and National Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Changsha, Hunan, 410011, China.
Background: The heterogeneity of cognitive impairments in schizophrenia has been widely observed. However, reliable cognitive boundaries to differentiate the subgroups remain elusive. The key challenge for cognitive subtyping is applying an integrated and standardized cognitive assessment and understanding the subgroup-specific neurobiological mechanisms.
View Article and Find Full Text PDFDiagnosing Helicobacter pylori using autoencoders and limited annotations through anomalous staining patterns in IHC whole slide images.
Int J Comput Assist Radiol Surg
January 2025
Comp. Sci. Dep, Universitat Autònoma de Barcelona, Campus UAB, Cerdanyola del Vallès, 08193, Catalunya, Spain.
Purpose: This work addresses the detection of Helicobacter pylori (H. pylori) in histological images with immunohistochemical staining. This analysis is a time-demanding task, currently done by an expert pathologist that visually inspects the samples.
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