A review of research on cytological approach in salivary gland masses.

Indian J Dent Res

Department of Oral Pathology and Microbiology, SVS Institute of Dental Sciences, Mahabubnagar, Telangana, India.

Published: September 2018

AI Article Synopsis

  • The study evaluated the diagnostic accuracy of fine-needle aspirations (FNAs) for salivary gland diseases by analyzing literature from 1980-2016, revealing 29 relevant studies out of 414 found.
  • The included studies, covering 5,274 cases, demonstrated FNAs have a high sensitivity (87%-100%) and specificity (90%-100%) in distinguishing between benign and malignant lesions.
  • The authors recommend standardized reporting protocols and checklists to improve consistency and clarity in future research on FNAs in salivary gland pathologies.

Article Abstract

To evaluate the diagnostic accuracy of fine-needle aspirations (FNAs) in salivary gland pathologies. A comprehensive literature search was conducted in the PubMed database using related Medical Subject Heading terms "sensitivity and specificity of FNA in salivary gland" and "diagnostic accuracy of FNA in salivary gland" for the period 1980-2016, and we found that 414 research studies had been published. PRISMA technology was utilized to prepare flow chart for displaying data search strategy. A total of 385 articles were excluded based on the established inclusion and exclusion criteria of the study. Twenty-nine research studies were included. Those twenty-nine studies on the sensitivity and specificity of FNAs in salivary gland pathology consisted of 5274 cases of benign, malignant and inflammatory salivary gland lesions. The present study identified a range of 87%-100% sensitivity and 90%-100% specificity for the usefulness of FNAs in distinguishing benign and malignant salivary gland lesions. Although a considerable number of studies have been identified that reported on sensitivity and specificity of FNAs in salivary gland pathologies, each study had a different approach in reporting the sensitivity and specificity. We emphasize that standardized reporting protocols of sensitivity and specificity report supported with checklists would help future researchers to interpret this cytological method and make more accurate clinical utility and usefulness reports on salivary gland pathologies.

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http://dx.doi.org/10.4103/ijdr.IJDR_190_17DOI Listing

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