In this issue of JEM, Balbinot et al. (https://doi.org/10.1084/jem.20170934) describe an original mechanism where inactivation regulates intestinal metaplastic to neoplastic transition in a paracrine fashion. Surprisingly, the target cells are neighboring "normal" Cdx2-positive cells.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839770 | PMC |
| http://dx.doi.org/10.1084/jem.20180215 | DOI Listing |
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