Omadacycline (OMC), a broad-spectrum aminomethylcycline, has shown clinical efficacy in anaerobic acute bacterial skin and skin structure infections (ABSSSI) and in animal models of intra-abdominal anaerobic infections. Here, the activity of OMC against clinically relevant anaerobes was similar to that of tigecycline, with MIC values of 1 to 8 μg/ml against spp., 0.5 μg/ml against , spp., and , 1 μg/ml against spp., and 16 μg/ml against .
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913939 | PMC |
| http://dx.doi.org/10.1128/AAC.00047-18 | DOI Listing |
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