Background And Objective: There is great interest, supported by clinical experience, in the relationship between Eating Disorders (EDs) and psychiatric symptoms and diseases. The psychopathology of EDs is also referred to many risk and protective factors, and there is some evidence in the literature, also about genetic and neurobiological factors involved. The aim of this review is to examine and synthesize the recent scientific literature on this topic, in particular the complex relationship between Anorexia Nervosa and Neuropsychiatric Disorders.
Methods: We analyzed the best of published literature on the topic, identifying keywords and MeSH terms in Pubmed and then searching them. The last search was performed on November 2017.
Results: Psychiatric comorbidities are very common in anorexia nervosa. Mood disorders, major depressive disorders, anxiety disorders, obsessive-compulsive disorders, developmental disorders among autistic spectrum and attention-deficit hyperactivity disorder and even some personality disorders, substance abuse and borderline traits have been reported, and some observations suggest a positive genetic correlation between anorexia nervosa and schizophrenia.
Conclusion: The great amount of scientific articles dealing with the relationship between EDs and psychopathology confirms the complexity of these problems and the difficulties in diagnosis and treatment. An accurate diagnosis and assessment of clinical risk about psychological, psychiatric, nutritional and somatic aspects are therefore essential for an appropriate therapeutic management of patients affected by anorexia nervosa.
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http://dx.doi.org/10.2174/1871530318666180213111637 | DOI Listing |
J Eat Disord
January 2025
GGZ Rivierduinen Eating Disorders Ursula, Sandifortdreef 19, 2333 AK, Leiden, The Netherlands.
Introduction: Overvaluation of shape and weight is a critical component in understanding and diagnosing eating disorders. While the transdiagnostic model states that overvaluation of shape and weight is the core pathology of all eating disorders, this concept is not a criterion for binge-eating disorder. The lack of recognition of overvaluation of shape and weight may lead to overlooking, and consequently failure to address this construct during treatment.
View Article and Find Full Text PDFEur Eat Disord Rev
January 2025
Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Objective: Anorexia nervosa (AN) is associated with disturbances in reward processing, cognitive control, and body image perception, implicating striatal dysfunction. Evidence suggests that underweight may modulate brain function in AN. We aimed to investigate whole-brain resting-state functional connectivity (rsFC) of the striatum in patients with AN while controlling for the acute effects of underweight.
View Article and Find Full Text PDFInt J Eat Disord
January 2025
Eating Disorders Clinical and Research Program, Massachusetts General Hospital, Boston, Massachusetts, USA.
Two recent review papers published in the International Journal of Eating Disorders have considerably elevated the rigor of scholarship on the comorbidity between autism spectrum disorder (ASD) and eating disorders. One paper reported that more than one-quarter of individuals with acute anorexia nervosa also have ASD, and that autistic traits are positively correlated with eating disorder psychopathology. The other paper reported that, compared to individuals with low autistic traits, those with high autistic traits report poorer experiences of eating disorder treatment, despite similar treatment outcomes.
View Article and Find Full Text PDFBJPsych Open
January 2025
Centre for Research in Eating and Weight Disorders, Institute of Psychiatry, Psychology & Neuroscience, King's College London, UK; and Vincent Square Eating Disorder Service, Central and North West London NHS Foundation Trust, UK.
Background: Research suggests that those caring for a loved one with an eating disorder in the UK report unmet needs and highlight areas for improvement. More research is needed to understand these experiences on a wider, national scale.
Aims: To disseminate a national survey for adults who had experience caring for a loved one with an eating disorder in the UK, informed by the findings of a smaller scale, qualitative study with parents, siblings and partners in the UK.
Front Child Adolesc Psychiatry
May 2024
Department of Psychiatry & Behavioral Sciences, School of Medicine, Duke University, Durham, NC, United States.
Objective: The aim of our study was to delineate the differences in demographics, comorbidities, and hospital outcomes by eating disorder types in adolescents and transitional-age youth (15-26 years), and measure the association with psychiatric comorbidities.
Methods: We conducted a cross-sectional study using the nationwide inpatient sample (2018-2019) and included 7,435 inpatients (age 12-24 years) with a primary diagnosis of eating disorders: anorexia nervosa (AN, 71.7%), bulimia nervosa (BN, 4.
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