AI Article Synopsis
- CSF circulation includes two main types: bulk flow and pulsatile flow, the latter being influenced by heartbeats and breathing.
- Recent studies highlight the importance of this pulsatile flow for maintaining brain health, linking it to blood flow and potential issues in diseases like multiple sclerosis and hypertension.
- The review covers the mechanisms behind CSF pulsation, its clinical relevance, and introduces the idea of measuring changes in the width of the subarachnoid space as a way to assess CSF pulsatility.
Article Abstract
In the cerebrospinal fluid (CSF) circulation, two components can be distinguished: bulk flow (circulation) and pulsatile flow (back and forth motion). CSF pulsatile flow is generated by both cardiac and respiratory cycles. Recent years have seen increased interest in cardiac- and respiratory-driven CSF pulsatility as an important component of cerebral homeostasis. CSF pulsatility is affected by cerebral arterial inflow and jugular outflow and potentially linked to white matter abnormalities in various diseases, such as multiple sclerosis or hypertension. In this review, we discuss the physiological mechanisms associated with CSF pulsation and its clinical significance. Finally, we explain the concept of using the oscillations of subarachnoid space width as a surrogate for CSF pulsatility.
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| http://dx.doi.org/10.1007/5584_2018_155 | DOI Listing |
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