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Interocular retinal asymmetry and cognitive frailty: A prospective cohort study.
Alzheimers Dement
December 2024
Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan.
Introduction: The retinal nerve fiber layer (RNFL) or ganglion cell-inner plexiform layer (GC-IPL) is associated with cognitive impairment. However, the relationship between retinal asymmetry and cognitive frailty (CF) remains unknown.
Methods: Two hundred twenty-two community-dwelling older adults were assessed starting in 2015 and underwent biennial cognitive and frailty evaluations until 2022.
Theory of molecular emission power spectra. III. Non-Hermitian interactions in multichromophoric systems coupled with polaritons.
J Chem Phys
December 2024
Institute of Atomic and Molecular Sciences, Academia Sinica, Taipei 10617, Taiwan.
Based on our previous study [Wang et al., J. Chem.
View Article and Find Full Text PDFTunable Electron Correlation in Epitaxial 1T-TaS Spirals.
Adv Mater
December 2024
Department of Materials Science & Engineering, National Tsing Hua University, Hsinchu, 30013, Taiwan.
Tantalum disulfide (1T-TaS), being a Mott insulator with strong electron correlation, is highlighted for diverse collective quantum states in the 2D lattice, including charge density wave (CDW), spin liquid, and unconventional superconductivity. The Mott physics embedded in the 2D triangular CDW lattice has raised debates on stacking-dependent properties because interlayer interactions are sensitive to van der Waals (vdW) spacing. However, control of interlayer distance remains a challenge.
View Article and Find Full Text PDFAldehyde dehydrogenases as drug targets for cancer: SAR and structural biology aspects for inhibitor design.
Bioorg Chem
December 2024
Department of Bioinformatics, School of Life Scicnces, Pondicherry University, Pondicherry 605014, India. Electronic address:
Aldehydes are organic compounds containing a carbonyl group found exogenously or produced by normal metabolic processes and their accumulation can lead to toxicity if not cleared. Aldehyde dehydrogenases (ALDHs) are NAD(P)-dependent enzymes that catalyze the oxidation of such aldehydes and prevent their accumulation. Along with this primary detoxification function, the known 19 human isoforms of ALDHs, which act on different substrates, are also involved in various physiological and developmental processes.
View Article and Find Full Text PDFInverse design in photonic crystals.
Nanophotonics
April 2024
State Key Laboratory of Surface Physics, Key Laboratory of Micro- and Nano-Photonic Structures (Ministry of Education), and Department of Physics, Fudan University, Shanghai 200433, China.
Photonic crystals are periodic dielectric structures that possess a wealth of physical characteristics. Owing to the unique way they interact with the light, they provide new degrees of freedom to precisely modulate the electromagnetic fields, and have received extensive research in both academia and industry. At the same time, fueled by the advances in computer science, inverse design strategies are gradually being used to efficiently produce on-demand devices in various domains.
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