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http://dx.doi.org/10.1016/j.aprim.2017.11.003 | DOI Listing |
Cancer Immunol Immunother
January 2025
Department of Oncology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, Jiangxi Province, China.
The combined use of tocilizumab (TCZ) and immune checkpoint inhibitors (ICIs) in cancer treatment is gaining attention, but preclinical studies are lacking. Our study aims to investigate the synergistic anti-tumor effect of TCZ combined with ICIs and its role in treating immune-related adverse events (irAEs). The clinical significance of high interleukin-6 (IL-6) expression in tumor patients was analyzed from the Cancer Genome Atlas (TCGA) database.
View Article and Find Full Text PDFIntegr Psychol Behav Sci
January 2025
University of Aberdeen, Aberdeen, United Kingdom.
This interview article explores how British anthropologist Tim Ingold's work can inspire innovation in mental health and the psy disciplines. Ingold critiques dominant biomedical and individualistic approaches, arguing for the importance of caring attentiveness and abolishing dichotomies like those between surface and depth, when engaging with people to understand and assist them. Instead, he suggests viewing human existence as correspondences with environmental, social, and relational others.
View Article and Find Full Text PDFAnn Surg Oncol
January 2025
Department of Surgery, University of California San Diego School of Medicine, San Diego, CA, USA.
Background: Textbook outcome (TO) has been utilized to assess the quality of surgical care. This study aimed to define TO rates for minimally invasive gastric gastrointestinal stromal tumor (GIST) resections in a bi-institutional cohort.
Methods: Patients with gastric GIST (≤ 5 cm) who underwent laparoscopic or robotic resection (January 2014 to January 2024) were retrospectively identified from two GIST centers.
Clin Exp Med
January 2025
Pediatrics, Western University, London, ON, Canada.
Sepsis is a major cause of morbidity and mortality worldwide. Among the various types of end-organ damage associated with sepsis, hepatic injury is linked to significantly higher mortality rates compared to dysfunction in other organ systems. This study aimed to investigate potential biomarkers of hepatic injury in sepsis patients through a multi-center, case-control approach.
View Article and Find Full Text PDFMikrochim Acta
January 2025
Department of Pulmonary and Critical Care Medicine, Quzhou People's Hospital, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou, 324000, China.
A smartphone-integrated colorimetric sensor is introduced for the rapid detection of phenolic compounds, including 8-hydroquinone (HQ), p-nitrophenol (NP), and catechol (CC). This sensor relies on the peroxidase-mimicking activity of aspartate-based metal-organic frameworks (MOFs) such as Cu-Asp, Ce-Asp, and Cu/Ce-Asp. These MOFs facilitate the oxidation of a colorless substrate, 3,3',5,5'-tetramethylbenzidine (TMB), by reactive oxygen species (ROS) derived from hydrogen peroxide (HO), resulting in the formation of blue-colored oxidized TMB (ox-TMB).
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!