We synthesized a new ratiometric fluorescent Cu probe, bearing a morpholine moiety for selective binding to lysosomes and two picolylamine arms for the specific chelation of divalent copper ions. The probe capability to detect lysosomal Cu was demonstrated in human differentiated neuroblastoma cells by confocal microscopy.
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| http://dx.doi.org/10.1021/acs.inorgchem.7b02720 | DOI Listing |
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