To identify high-risk locations (hotspots) of road traffic crashes (RTC) in a redeveloping area of Shanghai, for formulating relevant countermeasures in similar areas. After geocoding the crash locations on electronic map, assessment of spatial clustering of accidents and hotspots spatial densities was conducted following Moran's I method, the kernel density estimation, the Ripley's K-function and the network-based kernel density estimation (NKDE). A total of 21,679 RTC incidents resulting in 24,147 victims were recorded from 2010 to 2012. RTCs tended to occur among male (81.8%) aged 20-49 years old (84.9%) riding buses (60.1%) or electric bikes (16.1%) in working time (15%). The network spatial analysis pinpointed the hotspots of RTC at the street level in the Songjiang new urban area, and more RTCs occurred at road intersections than on road segments. Findings from this research may help the authorities develop efficient programmes to target high-risk locations and specific vulnerable populations.
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http://dx.doi.org/10.1080/17457300.2018.1431938 | DOI Listing |
Proc Natl Acad Sci U S A
January 2025
Department of Physics and Astronomy, University of California, Los Angeles, CA 90095.
The course of evolution is strongly shaped by interaction between mutations. Such epistasis can yield rugged sequence-function maps and constrain the availability of adaptive paths. While theoretical intuition is often built on global statistics of large, homogeneous model landscapes, mutagenesis measurements necessarily probe a limited neighborhood of a reference genotype.
View Article and Find Full Text PDFToxics
November 2024
Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200336, China.
Non-targeted screening (NTS) technology has been showing significant potential in identifying contaminants of emerging concern (CECs) in water and has attracted great attention in academia in recent years. It is a method that analyzes samples without pre-selecting substances, enabling the detection and identification of unknown compounds, which is crucial for environmental health and public protection. This study uses the Bibliometrix package in R 4.
View Article and Find Full Text PDFAnal Cell Pathol (Amst)
January 2025
Department of Burn Surgery, The First Affiliated Hospital of Naval Medical University, People's Republic of China, Research Unit of Key Techniques for Treatment of Burns and Combined Burns and Trauma Injury, Chinese Academy of Medical Sciences, No. 168 Changhai Road, Shanghai 200433, China.
Trauma and burns are leading causes of death and significant global health concerns. RNA-binding proteins (RBPs) play a crucial role in post-transcriptional gene regulation, influencing various biological processes of cellular RNAs. This study aims to review the emerging trends and key areas of research on RBPs in the context of trauma and burns.
View Article and Find Full Text PDFJ Hazard Mater
December 2024
Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, P.O. Box 55760, Riyadh 11451, Saudi Arabia.
Human activities have far-reaching impact on natural ecosystems, causing increasing disturbances and disruptions to the delicate balance of the environment. Poor land use planning, urbanization, infrastructure development, and unplanned tourism exacerbate contamination and degradation in tourist destinations, yet the pollution of potentially toxic elements (PTEs) in these environments remains inadequately explored. To address this issue, we investigated the concentrations of acid-digested PTEs in road dust in Abbottabad city (Pakistan) with heavy traffic.
View Article and Find Full Text PDFSci Rep
December 2024
British Antarctic Survey, High Cross, Madingley Road, Cambridge, UK.
Marine microplastic is pervasive, polluting the remotest ecosystems including the Southern Ocean. Since this region is already undergoing climatic changes, the additional stress of microplastic pollution on the ecosystem should not be considered in isolation. We identify potential hotspot areas of ecological impact from a spatial overlap analysis of multiple data sets to understand where marine biota are likely to interact with local microplastic emissions (from ship traffic and human populations associated with scientific research and tourism).
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