Background: According to the guidelines aortoiliac TASC D lesions should be treated by bypass. The purpose of this study was to examine the results of hybrid procedures with the use of a self-expanding covered heparin-bonded stent graft (Viabahn) in patients with extensive aorto-iliac lesions who were not considered to be suitable for open aorto-iliac surgery.
Methods: All patients who received a hybrid procedure in combination with a Viabahn stent in our clinic to treat aortoiliac lesions between October 2011 and April 2017 were included in this retrospective analysis. Study endpoints were primary patency, amputation-free survival (AFS) and major adverse limb event (MALE) free survival after 2 years.
Results: We included 23 hybrid procedures (endarterectomy of the common femoral artery or cross over bypass and aortoiliac stent) in 20 patients (median age 59 years). Indication was critical limb ischemia in 70.0%. The reasons why patients were on high risk for alternative open aortoiliac revascularization were hostile abdomen in 35.0%, cardiopulmonary contraindications in 35%, cancer in 10.0%, age >80 years in 10.0% and alcoholic cirrhosis in 10.0%. The 30-day mortality was 15.0%, the major amputation rate was 4.3%. We had no early graft occlusion. After 2 years primary patency was 100%, AFS 58.2% and MALE free survival 95.7%.
Conclusions: A hybrid procedure with the use of a Viabahn stent in severe aortoiliac pathologies showed good patency results in this selected patient group. Therefore, it should be considered a feasible alternative to aortoiliac bypass surgery in surgical high-risk patients.
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http://dx.doi.org/10.23736/S0021-9509.18.10295-3 | DOI Listing |
Spine (Phila Pa 1976)
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Indiana Spine Group Location of investigation Indiana Spine Group, 13225 N. Meridian Street, Carmel, IN 46032.
Study Design: Retrospective cohort.
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Research (Wash D C)
January 2025
Department of Electrical and Computer Engineering, National University of Singapore, Singapore 117583, Singapore.
Recent advancements in nanotechnology have revolutionized terahertz (THz) technology. By enabling the creation of compact, efficient devices through nanoscale structures, such as nano-thick heterostructures, metasurfaces, and hybrid systems, these innovations offer unprecedented control over THz wave generation and modulation. This has led to substantial enhancements in THz spectroscopy, imaging, and especially bio-applications, providing higher resolution and sensitivity.
View Article and Find Full Text PDFRSC Adv
January 2025
Department of Chemical and Materials Engineering, School of Engineering and Digital Sciences, Nazarbayev University Astana Kazakhstan
Sodium-ion batteries (SIBs) offer several advantages over traditional lithium-ion batteries, including a more uniform sodium distribution, lower-cost materials, and safer transportation options. A promising development in SIBs is the use of hard carbons as anode materials due to their low insertion voltage and larger interlayer spacing, which improve sodium-ion insertion. Traditionally, hard carbons are made from costly carbon sources, but recent advancements have focussed on using abundant bio-waste, like coffee grounds.
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January 2025
School of Life Sciences, Tiangong University, Tianjin 300387, China.
Objective: The objective of this research is to enhance pneumonia detection in chest X-rays by leveraging a novel hybrid deep learning model that combines Convolutional Neural Networks (CNNs) with modified Swin Transformer blocks. This study aims to significantly improve diagnostic accuracy, reduce misclassifications, and provide a robust, deployable solution for underdeveloped regions where access to conventional diagnostics and treatment is limited.
Methods: The study developed a hybrid model architecture integrating CNNs with modified Swin Transformer blocks to work seamlessly within the same model.
Small Methods
January 2025
Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Innovative Drug Research Center, School of Pharmaceutical Sciences, Chongqing University, Chongqing, 401331, China.
Deoxyribonucleic acid (DNA), a fundamental biomacromolecule in living organisms, serves as the carrier of genetic information. Beyond its role in encoding biological functions, DNA's inherent ability to hybridize through base pairing has opened new avenues for its application in biological sciences. This review introduces DNA nanotechnology and DNA-encoded library (DEL), and highlights their shared design principles related to DNA assembly.
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