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Novel Otolaryngological and Radiological Manifestations in GAPO Syndrome.
Ear Nose Throat J
December 2024
Department of Otorhinolaryngology, Al Mouwasat University Hospital, Damascus University, Damascus, Syria.
GAPO syndrome is an exceptionally-rare autosomal recessive disorder characterized by growth retardation, alopecia, pseudoanodontia, and optic abnormalities, with fewer than 60 cases reported globally. We present the first documented case in Syria, highlighting novel otolaryngological and radiological findings that expand the clinical spectrum of this syndrome. A 27-year-old male presented with chronic right-sided otalgia, unilateral conductive hearing loss, and persistent sinonasal symptoms.
View Article and Find Full Text PDFComparison of Eosinophil Profile and Lund Kennedy Score in Patients with Nasal Polyps.
Indian J Otolaryngol Head Neck Surg
December 2024
Government Medical College Srinagar, House No. 1, Block C, Budshah Nagar Natipora, Srinagar, Jammu and Kashmir India.
Article Synopsis
- Nasal polyps are non-cancerous growths in the nasal cavity, often linked to damage in the nasal mucosa and characterized by a high presence of eosinophils, which are inflammatory cells.
- A study was conducted on 62 ENT patients at a medical college, focusing on their age, eosinophil counts, and Lund Kennedy scores to assess the severity of their nasal polyps.
- Results showed a positive relationship between higher levels of tissue and peripheral eosinophils and increased severity of nasal polyps, as well as a tendency for the disease to occur more frequently in males.
[BRONCHOPULMONARY ASPERGILLOSIS WITH COMORBID GRANULOMATOUS POLYANGIITIS IN A PATIENT WHO PRESENTED WITH EXOPHTHALMOS: A CASE REPORT].
Arerugi
September 2024
Department of Respiratory Medicine and Allergology, Nagoya City University Hospital.
There have been no reports of the coexistence of allergic bronchopulmonary aspergillosis (ABPA) and granulomatosis with polyangiitis (GPA). The first case of ABPA with comorbid GPA that developed exophthalmos is reported. A 69-year-old man was referred to our hospital for exophthalmos, fever, anorexia and weight loss.
View Article and Find Full Text PDFA proposal for analyzing the inflammatory and remodeling processes of mucosa in chronic rhinosinusitis with nasal polyposis through MRI.
Braz J Otorhinolaryngol
November 2024
Universidade Federal de São Paulo, Departamento de Otorrinolaringologia-Cirurgia de Cabeça e Pescoço, São Paulo, SP, Brazil; University of British Columbia, Division of Rhinology, Vancouver, Canada.
Objectives: Chronic Rhinosinusitis with Nasal Polyposis (CRSwNP) is a disease characterized by chronic inflammation and tissue remodeling process. The remodeling process in nasal polyps has mainly been studied by histology analysis. However, it is limited to a polyp fragment and requires tissue removal.
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