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Article Synopsis
  • A 35-year-old woman was admitted to the hospital with severe consciousness disturbances and fever, but initial tests including MRI revealed brain lesions without a clear cause or infection.
  • Diagnosed with probable limbic encephalitis and drug-resistant epilepsy, she underwent treatments like immunoglobulin cycles and plasmapheresis, followed by antiepileptic medications and psychiatric care.
  • After treatment, the patient experienced some improvements in memory and the reduction of psychotic symptoms and seizures, highlighting the complexity of her condition and the challenges in achieving effective treatment.
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Objective: This study aimed to explore the application effect of repetitive transcranial magnetic stimulation (rTMS) combined with tiapride hydrochloride tablets in children with attention deficit hyperactivity disorder (ADHD).

Methods: The medical records of 197 children with ADHD in our hospital from January 2022 to January 2023 were retrospectively analysed. Seven children who did not meet the inclusion criteria were excluded, and 190 children were finally included in this retrospective study.

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Article Synopsis
  • Acori graminei Rhizoma, a traditional Chinese medicine, contains calamus volatile oil which shows potential in protecting nerve cells and improving learning and memory, though its specific anti-tic effects remain unclear.
  • The study investigates the impact of Volatile Oil from Acori Tatarinowii on dopamine and glutamate systems in rats with Tic Disorder, aiming to reveal its underlying pharmaceutical mechanisms.
  • Using various research methods, including behavioral assessments and molecular analysis, the study measures changes in neuronal structure and neurotransmitter levels, helping to understand how this herbal treatment affects Tic Disorder.
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An update on the pharmacological management of Tourette syndrome and emerging treatment paradigms.

Expert Rev Neurother

October 2024

Department of Neurology, Parkinson's Disease Center and Movement Disorders Clinic, Baylor College of Medicine, Houston, TX, USA.

Article Synopsis
  • Tourette syndrome (TS) is a childhood-onset disorder with tics, and medication is recommended when symptoms significantly impact life quality.
  • The article reviews the types of tics, diagnostic criteria, and various pharmacotherapy options, including those currently being researched.
  • Individualized treatment plans are crucial; behavioral therapy is the first choice, while medications like alpha-2 agonists, antipsychotics, and botulinum toxin injections may be considered based on severity and side effects.
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Annually, 172 million fall events cause temporary or permanent impairment in older adults, and this number is increasing. Contributing factors that increase the risk for falls include age, polypharmacy, and malnutrition. This study evaluated medications mainly included in the EU(7)-PIM (potentially inappropriate medication) list.

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