Background: Recently a multispecialty, multinational task force convened to redefine the criteria for organ dysfunction, sepsis, severe sepsis, and septic shock. The study recommended the quick sequential organ failure assessment (qSOFA) score to identify sepsis patients. The qSOFA is felt to be the initial screen to prompt a more in-depth sepsis workup. This may be particularly true in resource-limited environments such as the prehospital arena.
Objectives: The goal of this study was to identify whether emergency medical services (EMS) patients who met all three qSOFA criteria correlated with an emergency department (ED) identification of sepsis.
Methods: This was a retrospective chart review of adult patients≥18years of age, meeting qSOFA criteria and presenting to the emergency department between 1/01/2014 and 6/30/2016. Subjects were identified through an electronic query of the EMS record repository.
Results: 72 subjects were included in the final analysis. Subjects in the septic group tended to be older with a mean age of 72years vs 64years. There was no observed discrepancy relating to gender. 48 of the subjects (67%) were identified as septic and 24 (33%) were identified as non-septic after review of the ED chart. This yielded a positive predictive value of the prehospital qSOFA as 66.67% (95% CI 55.8-77.6).
Conclusions: EMS patients with positive qSOFA screens were more likely to be septic upon disposition to the ED.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.ajem.2018.01.073 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Urinary biomarkers for diagnosing acute kidney injury in sepsis in the emergency department.
Heliyon
January 2025
Department of Emergency Medicine, Seoul National University Bundang Hospital (SNUBH), Seongnam-si, South Korea.
Background: Development of acute kidney injury (AKI) in patients with sepsis is associated with increased mortality, highlighting the importance of early detection and management. However, baseline creatinine or urine output measurements are required for AKI diagnosis, which can be challenging in emergency departments (EDs). We aimed to evaluate the association between urinary biomarkers and the AKI diagnosis or 30-day survival status in patients with sepsis in the ED.
View Article and Find Full Text PDFNitric oxide modulates contrast suppression in a subset of mouse retinal ganglion cells.
Elife
January 2025
Werner Reichardt Centre for Integrative Neuroscience, University of Tübingen, Tübingen, Germany.
Neuromodulators have major influences on the regulation of neural circuit activity across the nervous system. Nitric oxide (NO) has been shown to be a prominent neuromodulator in many circuits and has been extensively studied in the retina. Here, it has been associated with the regulation of light adaptation, gain control, and gap junctional coupling, but its effect on the retinal output, specifically on the different types of retinal ganglion cells (RGCs), is still poorly understood.
View Article and Find Full Text PDFComparative Assessment of the qSOFA, SII, dNLR, and OISS Infection Severity Scores in Diabetic Versus Non-Diabetic Patients with Odontogenic Infections.
Biomedicines
November 2024
Department of Odontotherapy and Endodontics, Faculty of Dental Medicine, "Victor Babes" University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square 2, 300041 Timisoara, Romania.
Odontogenic infections (OIs) can progress rapidly and may lead to severe systemic complications, especially in patients with underlying conditions like diabetes mellitus (DM). This study aims to evaluate the predictive value of inflammatory scores-quick Sequential Organ Failure Assessment (qSOFA), Systemic Immune-Inflammation Index (SII), derived Neutrophil-to-Lymphocyte Ratio (dNLR), and Odontogenic Infection Severity Score (OISS)-in assessing the severity of OIs in diabetic versus non-diabetic patients. A case-control study was conducted on 123 patients diagnosed with OIs.
View Article and Find Full Text PDFReal-time estimated Sequential Organ Failure Assessment (SOFA) score with intervals: improved risk monitoring with estimated uncertainty in health condition for patients in intensive care units.
Health Inf Sci Syst
December 2025
Department of Cardiac, Thoracic and Vascular Surgery, National University Hospital, Singapore, Singapore.
Article Synopsis
- Real-time risk monitoring is essential in ICUs but often struggles with a lack of updates for clinical variables, prompting the development of a new framework that incorporates uncertainties into existing risk assessment systems like the SOFA score.
- The study analyzed data from 5,351 patients in a Cardiothoracic ICU, utilizing machine learning models to enhance real-time SOFA scores and account for uncertainties, with validation showing improved predictive capabilities for mortality and readmission.
- Results demonstrated that the new model outperformed traditional SOFA scores and quick SOFA in predicting outcomes, suggesting it could lead to more efficient testing and better patient care in clinical settings.
Early warning systems for identifying severe maternal outcomes: findings from the WHO global maternal sepsis study.
EClinicalMedicine
January 2025
Malawi-Liverpool Wellcome Programme, Blantyre, Malawi.
Background: Infections and sepsis are leading causes of morbidity and mortality in women during pregnancy and the post-pregnancy period. Using data from the 2017 WHO Global Maternal Sepsis Study, we explored the use of early warning systems (EWS) in women at risk of sepsis-related severe maternal outcomes.
Methods: On April 27, 2023, we searched the literature for EWS in clinical use or research in obstetric populations.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!