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Dengue virus non-structural protein 1 binding to thrombin as a dengue severity marker: Comprehensive patient analysis in south Taiwan.
J Microbiol Immunol Infect
December 2024
Center of Infectious Disease and Signaling Research, National Cheng Kung University, Tainan, Taiwan; Department of Pediatrics, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, 704, Taiwan; Department of Pediatrics, National Cheng Kung University Hospital Dou-Liou Branch, College of Medicine, National Cheng Kung University, Yunlin 640, Taiwan. Electronic address:
Background: Previously we identified a complex of non-structural protein (NS) 1 - Thrombin (NST) in dengue infected patients. Here, we investigated how the concentration of NS1 and NST differ in various dengue severity levels as well as their demographic and clinical features. Several comorbid (hypertension, diabetes, and chronic renal failure) often found in dengue patients were also measured and analyzed.
View Article and Find Full Text PDFCognitive decline and neuroinflammation in a mouse model of obesity: An accelerating role of ageing.
Brain Behav Immun
December 2024
Department of Geriatrics, University Medical Center Goettingen, Robert-Koch-Str. 42, 37075 Goettingen, Germany; DZHK (German Center for Cardiovascular Research), Partner Site Göttingen, 37075 Göttingen, Germany. Electronic address:
Obesity, a pandemic, worldwide afflicts almost one billion people. Obesity and ageing share several pathological pathways leading to neurological disorders. However, due to a lack of suitable animal models, the long-term effects of obesity on age-related disorders- cognitive impairment and dementia have not yet been thoroughly investigated.
View Article and Find Full Text PDFA Cross-Sectional Serological Study to Assess the Prevalence and Risk Factors of Anaplasmosis in Dromedary Camels in Punjab, Pakistan.
Vet Sci
December 2024
Department of Clinical Medicine and Surgery, Faculty of Veterinary Science, University of Agriculture, Faisalabad, Pakistan.
Anaplasmosis is an infectious disease transmitted by ticks and caused by obligate intracellular pathogen of belonging to genus Infections of one-humped camels () and llamas () have been reported previously. The aim of this study was to investigate the seroprevalence and risk factors of anti- spp. antibodies in of the Punjab, Pakistan.
View Article and Find Full Text PDFInfection Rate and Risk Factors of SARS-CoV-2 Infection in Retail Workers at the Onset of the COVID-19 Pandemic, Quebec, Canada.
Infect Dis Rep
December 2024
Infectious Diseases Research Center of Laval University, CHU de Québec-Université Laval (CHUL Hospital), Quebec City, QC G1V 4G2, Canada.
During the pandemic, client-facing workers were perceived to be at greater risk of SARS-CoV-2 infection. This study investigated the risk factors for SARS-CoV-2 infection among a cohort of 304 retail workers in the Quebec City metropolitan area. After providing consent, participants were interviewed to gather information on demographic, socioeconomic, behavioural, and occupational variables.
View Article and Find Full Text PDFBackground: Sheep scab, caused by the highly infectious mite, is considered to be endemic in Northern Ireland, although little investigation has been reported. A pilot project was undertaken to engage farmers, confirm cases with diagnostic methods and identify specific barriers to control, with the aim of informing future control programmes.
Methods: Through farmers self-reporting suspected outbreaks, on-farm risk assessments and clinical investigations were carried out by the farm's veterinary surgeon, who utilised light microscopy and serological testing to diagnose scab.
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