For "The Year That Was 2017," I have selected 3 papers in the area of growth, maturation, and exercise during youth. The first paper has been chosen because it provides for the first time the relative age, maturation, and anthropometric biases on position allocation in elite youth soccer players participating in talent identification programs in professional soccer league. Specific anthropometrical attributes characterized playing positions with a bias toward these athletes who are comparatively tall and heavy for their age already in younger ages, whereas position-specific physical attributes do not become apparent until the later stages of talent development. The second paper was selected because it provides a unique perspective on the contributions of different types of sport activities to the development of soccer performance. This paper demonstrated that early specialization and concentration on one sport only during growth is not beneficial in elite youth soccer. In contrast, variable early sporting experience, and not different physiological parameters, facilitates subsequent soccer performance development. The third paper provided some evidence that the consequence of physical activity during adolescence can be far reaching as physical activity might not only predict academic success during compulsory basic education but also boost educational outcomes in adulthood.
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http://dx.doi.org/10.1123/pes.2017-0291 | DOI Listing |
Bone
December 2024
State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan 430079, China. Electronic address:
Endochondral ossification (EO) is a pivotal process during fracture healing and traumatic heterotopic ossification (HO), involving the cartilaginous matrix synthesis and mineralization. Unlike the extracellular matrix, the hyaluronan (HA)-rich pericellular matrix (PCM) directly envelops chondrocytes, serving as the frontline for extracellular signal reception and undergoing dynamic remodeling. Pentraxin 3 (PTX3), a secreted glycoprotein, facilitates HA matrix assembly and remodeling.
View Article and Find Full Text PDFPoult Sci
December 2024
Laboratory of Regional Center of Excellence for Poultry Science, University of Lomé, 01 BP 1515, Lomé, Togo.
The present study examined the effects of breeder age and oxygen (O₂) concentrations during the late chorioallantoic membrane (CAM) growth stage on embryo development, hatching dynamics, chick quality, bone mineralization and hatchability. A total of 1200 eggs from 33- and 50-week-old ISA layer breeders, weighing 53.85 g and 60.
View Article and Find Full Text PDFPhytomedicine
December 2024
Jinan Central Hospital, Shandong First Medical University, Jinan 250013, Shandong, China. Electronic address:
Background: The dysregulation of ribosome biogenesis has been extensively identified in various cancers, making it emerge as a hallmark of malignant cells. This highlights the potential of targeting ribosome biogenesis as an effective approach for treating cancer patients. Although chemotherapy drugs including doxorubicin and cisplatin often target ribosome biogenesis to induce DNA damage or inhibit tumor cell proliferation, they are associated with significant side effects.
View Article and Find Full Text PDFCompr Rev Food Sci Food Saf
January 2025
School of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, Singapore, Singapore.
Cultivated meat, produced using cell culture technology, is an alternative to conventional meat production that avoids the risks from enteric pathogens associated with animal slaughter and processing. Cultivated meat therefore has significant theoretical microbiological safety advantages, though limited information is available to validate this. This review discusses sources and vectors of microbial contamination throughout cultivated meat production, introduces industry survey data to evaluate current industry practices for monitoring and mitigating these hazards, and highlights future research needs.
View Article and Find Full Text PDFJ Transl Med
December 2024
Department of Pediatric Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, 430022, Hubei Province, People's Republic of China.
Background: Neuroblastoma (NB), the most prevalent solid tumor in children, arises from sympathetic nervous system and accounts for 15% of pediatric cancer mortality. This malignancy exhibits substantial genetic and clinical heterogeneity, thus complicating treatment strategies. Poly(ADP-ribose) polymerase 1 (PARP1), a key enzyme catalyzing polyADP-ribosylation (PARylation), plays critical roles in various cellular processes, and contributes to tumorigenesis and aggressiveness.
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