AI Article Synopsis
- Autism spectrum disorder (ASD) is a developmental disorder identified in 1943, primarily affecting social interaction and communication, often recognized by the age of 18 months.
- Genetic factors play a significant role in ASD, with various associated syndromes, while non-genetic and environmental factors are also implicated.
- Current studies examine the genetic, neurophysiological, and neurochemical aspects of autism, revealing structural brain abnormalities and alterations in neurotransmitter systems.
Article Abstract
The autism spectrum disorder (ASD) was described in 1943 and is defined as a developmental disorder that affects social interaction and communication. It is usually identified in early stages of development from 18 months of age. Currently, autism is considered a neurological disorder with a spectrum covering cases of different degrees, which is associated with genetic factors, not genetic and environmental. Among the genetic factors, various syndromes have been described that are associated with this disorder. Also, the neurobiology of autism has been studied at the genetic, neurophysiological, neurochemical and neuropathological levels. Neuroimaging techniques have shown multiple structural abnormalities in these patients. There have also been changes in the serotonergic, GABAergic, catecholaminergic and cholinergic systems related to this disorder. This paper presents an update of the information presented in the genetic and neuroendocrine aspects of autism spectrum disorder.
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| http://dx.doi.org/10.1016/j.bmhimx.2015.01.010 | DOI Listing |
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