[This corrects the article DOI: 10.1371/journal.pone.0189147.].
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805353 | PMC |
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0192815 | PLOS |
JMIR Aging
January 2025
Institute of Mathematics and Computer Sciences, University of São Paulo, São Carlos SP, Brazil.
Background: The prevalence of stroke is high in both males and females, and it rises with age. Stroke often leads to sensor and motor issues, such as hemiparesis affecting one side of the body. Poststroke patients require torso stabilization exercises, but maintaining proper posture can be challenging due to their condition.
View Article and Find Full Text PDFNat Commun
January 2025
Department of Biology, University of Konstanz, Konstanz, Germany.
Phosphorylation of substrates by cyclin-dependent kinases (CDKs) is the driving force of cell cycle progression. Several CDK-activating cyclins are involved, yet how they contribute to substrate specificity is still poorly understood. Here, we discover that a positively charged pocket in cyclin B1, which is exclusively conserved within B-type cyclins and binds phosphorylated serine- or threonine-residues, is essential for correct execution of mitosis.
View Article and Find Full Text PDFJ Chem Inf Model
January 2025
Digital Medical Research Center, School of Basic Medical Sciences, Fudan University, Shanghai 200032, P. R. China.
Predicting the docking conformation of a ligand in the protein binding site (pocket), i.e., protein-ligand docking, is crucial for drug discovery.
View Article and Find Full Text PDFJAMA Netw Open
January 2025
Division of General Internal Medicine and Primary Care, Brigham and Women's Hospital, Boston, Massachusetts.
Importance: Nearly all Medicare Advantage (MA) plans offer dental, vision, and hearing benefits not covered by traditional Medicare (TM). However, little is known about MA enrollees' use of those benefits or how much they cost MA insurers or enrollees.
Objective: To estimate use, out-of-pocket (OOP) spending, and insurer payments for dental, hearing, and vision services among Medicare beneficiaries.
J Conserv Dent Endod
November 2024
Department of Conservative Dentistry and Endodontics, K. M. Shah Dental College and Hospital, Sumandeep Vidyapeeth Deemed to be University, Vadodara, Gujarat, India.
Aim: The aim of the study was to compare and evaluate proximal contact tightness and contours using two newer contact-forming systems in Class II composite restorations.
Materials And Methods: After institutional ethical approval and Clinical Trials Registry-India registration, patients were chosen according to the inclusion-exclusion criteria with informed consent. A total of 60 patients were randomly assigned to two groups.
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