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Orally administered prednisolone decreases plasma arginine vasopressin and serum copeptin concentrations in healthy dogs.
J Vet Intern Med
January 2025
Department of Small Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Background: The pathophysiology of polyuria and polydipsia secondary to exogenous glucocorticoid excess is incompletely understood.
Objective: Investigate plasma AVP (pAVP) and serum CoP (sCoP) concentrations in healthy dogs before, during, and after abrupt discontinuation of a long-term course of orally administered prednisolone.
Animals: Eight healthy neutered young adult research Beagles.
The influence of ammonia-N and salinity levels on oxidative stress markers, hepatic enzymes, and acid phosphatase activity in Nile tilapia (Oreochromis niloticus).
Sci Rep
January 2025
Department of Fisheries, Faculty of Natural Resources, Isfahan University of Technology, Isfahan, 84156-8311, Iran.
The point of our study was to examine the interaction of ammonia-N poisoning and salinity on serum enzymes and oxidative stress factors of blood and liver in Nile tilapia (Oreochromis niloticus). The 50% lethal concentration (LC) in 96 h was 0.86 mg/L of ammonia-N.
View Article and Find Full Text PDFSalivary pH, but not conductivity, is an indicator of diarrhea in neonatal calves.
Front Vet Sci
December 2024
Scotland's Rural College (SRUC), Edinburgh, United Kingdom.
Article Synopsis
- Neonatal calf diarrhea frequently leads to dehydration and metabolic acidosis, impacting calf mortality, growth, and productivity, prompting interest in technological disease detection.
- The study explored the relationship between saliva conductivity and pH with clinical and biochemical indicators in calves, assessing the health of 141 dairy-bred calves from one week old until 25 days or until they developed diarrhea.
- Results indicated that while saliva pH decreased in calves with diarrhea, saliva conductivity showed no correlation with diarrhea or dehydration, highlighting the complexity of hydration status assessments in these animals.
Multi-environment and multi-parameter screening of stability and coating efficiency of gold nanoparticle bioconjugates in application media.
Sci Rep
December 2024
Department of Chemistry G. Ciamician, University of Bologna, Bologna, 40126, Italy.
Gold nanoparticles (AuNPs) and their biocompatible conjugates find wide use as transducers in (bio)sensors and as Nano-pharmaceutics. The study of the interaction between AuNPs and proteins in representative application media helps to better understand their intrinsic behaviors. A multi-environment, multi-parameter screening strategy is proposed based on asymmetric flow field flow fractionation (AF4)-multidetector.
View Article and Find Full Text PDFRedefining Diagnostic Cut-Offs for the Indirect Water Deprivation Test.
Clin Endocrinol (Oxf)
February 2025
Division of Diabetes, Endocrinology and Metabolism, Department of Metabolism Digestion and Reproduction, Imperial College London, London, UK.
Objective: An incorrect diagnosis of arginine vasopressin deficiency and resistance (AVP-D and AVP-R) results in the potentially dangerous use of desmopressin in healthy individuals. The water deprivation test is a central diagnostic test in patients with polydipsia polyuria syndrome (PPS). This study aims to determine the effectiveness of the current interpretation of reference ranges.
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