Cutaneous disorders characterized by elastolysis or loss of elastic tissue.

J Dtsch Dermatol Ges

Department of Dermatology, Venereology, and Allergology, HELIOS Medical Center Hildesheim, Hildesheim, Germany.

Published: February 2018

Along with collagen, elastic fibers are integral components of cutaneous connective tissue. A decrease in elastic fibers or loss thereof has been described in a number of clinically distinct skin diseases, both hereditary and acquired. In disorders associated with inflammation, elastophagocytosis is an important histological hallmark. Treatment is generally difficult.

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http://dx.doi.org/10.1111/ddg.13430DOI Listing

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