[Nextflow, an efficient tool to improve computation numerical stability in genomic analysis].

Biol Aujourdhui

Comparative Bioinformatics Group, Bioinformatics and Genomics Programme, Center for Genomic Regulation (CRG), Dr Aiguader, 88, 08003 Barcelona, Spain - Universitat Pompeu Fabra (UPF), Barcelona, Spain.

Published: August 2018

Reproducing routine bioinformatics analysis is challenging owing to a combination of factors hard to control for. Nextflow is a flow management framework that uses container technology to insure efficient deployment and reproducibility of computational analysis pipelines. Third party pipelines can be ported into Nextflow with minimum re-coding. We used RNA-Seq quantification, genome annotation and phylogeny reconstruction examples to show how two seemingly irreproducible analyzes can be made stable across platforms when ported into Nextflow.

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Source
http://dx.doi.org/10.1051/jbio/2017029DOI Listing

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