The original version of this article unfortunately contained a mistake in the author group section. Author A. Bronowicka-Szydełko's surname was inadvertently interchanged to "Szydełko-Bronowicka".
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http://dx.doi.org/10.1007/s10719-018-9813-z | DOI Listing |
Epilepsia
March 2025
Departamento de Neurologia e Neurocirurgia, Escola Paulista de Medicina, Universidade Federal de São Paulo (Unifesp), São Paulo, Brazil.
The immune system is crucial for the correct brain development, and recent findings also point toward central control of immune response. As the immune system is not fully developed at birth, the early years become an important window for infections and for the development of epilepsy. Both central and even peripheral inflammation may impact brain function, promoting opening of the blood-brain/blood and cerebrospinal barriers and allowing entry of immune cells and cytokines, which in turn may affect neuron function and connections.
View Article and Find Full Text PDFAdv Mater
March 2025
Centre for Craniofacial and Regenerative Biology, King's College London, London, SE1 1UL, UK.
Base editing, a CRISPR-based genome editing technology, enables precise correction of single-nucleotide variants, promising resolutive treatment for monogenic genetic disorders like recessive dystrophic epidermolysis bullosa (RDEB). However, the application of base editors in cell manufacturing is hindered by inconsistent efficiency and high costs, contributed by suboptimal delivery methods. Nanoneedles have emerged as an effective delivery approach, enabling highly efficient, non-perturbing gene therapies both in vitro and in vivo.
View Article and Find Full Text PDFJ Opioid Manag
March 2025
Department of Clinical Pharmacy Research and Education, Osaka University Graduate School of Pharmaceutical Sciences, Suita, Osaka, Japan.
Objective: Methadone may cause detrimental side effects such as corrected QT (QTc) prolongation. However, methadone may be desirable in patients with advanced cancer and those with heart disease who have intractable pain. Therefore, we aimed to evaluate the safety and efficacy of initiating methadone for cancer pain in patients at high risk of methadone-induced QTc prolongation.
View Article and Find Full Text PDFACS Electrochem
March 2025
Institute of Physical Chemistry, University of Innsbruck, Innrain 52c, A-6020 Innsbruck, Austria.
Solid oxide cell technologies play a crucial role in climate change mitigation by enabling the reversible storage of renewable energy. Understanding the electrochemical high-temperature reaction mechanisms and the catalytic role of the electrode and electrolyte materials is essential for advancing power-to-H technologies. Despite its significance, limited spectroscopic research focusing on nickel and yttria-stabilized zirconia (Ni/YSZ) is available.
View Article and Find Full Text PDFCureus
February 2025
Department of General Medicine, Saga University Hospital, Saga, JPN.
Infective endocarditis (IE) often presents as a fever of unknown origin due to its extremely diverse clinical presentations, requiring diverse advanced medical equipment and tests to make a correct diagnosis. Whether a physician can suspect IE in a clinical setting is dependent on the physician's knowledge and experience. If IE is not suspected, antibiotics are administered without obtaining blood cultures, complicating the clinical course and prognosis.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!