[Purpose] The purpose is to verify the effectiveness of the 2-step test in predicting cognitive decline in elderly individuals. [Subjects and Methods] One hundred eighty-two participants aged over 65 years underwent the 2-step test, cognitive function tests and higher level competence testing. Participants were classified as Robust, <1.3, and <1.1 using criteria regarding the locomotive syndrome risk stage for the 2-step test, variables were compared between groups. In addition, ordered logistic analysis was used to analyze cognitive functions as independent variables in the three groups, using the 2-step test results as the dependent variable, with age, gender, etc. as adjustment factors. [Results] In the crude data, the <1.3 and <1.1 groups were older and displayed lower motor and cognitive functions than did the Robust group. Furthermore, the <1.3 group exhibited significantly lower memory retention than did the Robust group. The 2-step test was related to the Stroop test (β: 0.06, 95% confidence interval: 0.01-0.12). [Conclusion] The finding is that the risk stage of the 2-step test is related to cognitive functions, even at an initial risk stage. The 2-step test may help with earlier detection and implementation of prevention measures for locomotive syndrome and mild cognitive impairment.
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http://dx.doi.org/10.1589/jpts.30.145 | DOI Listing |
Importance: Little is known about the spatial accessibility to dental clinics across the US.
Objective: To map the spatial accessibility of dental clinics nationally and to examine the characteristics of counties and US Census block groups with dental care shortage areas.
Design, Setting, And Participants: Cross-sectional study of US dental clinics in 2023 using data from the IQVIA national practitioners' database, which includes 205 762 active dentists.
J Dairy Sci
December 2024
University of Liège, Gembloux Agro-Bio Tech (ULiège-GxABT), 5030 Gembloux, Belgium.
Numerous prediction equations have been developed based on mid-infrared (MIR) spectra and some could be potentially used as biomarkers of heat stress. However, practical experience shows that confusion between the effect of heat stress and other effects like lactation stage or feeding variation over the year can easily occur. On this basis, the objective of this study was to identify potential milk components predicted by MIR as biomarkers of heat stress based on a 2-step approach allowing to correct for those effects.
View Article and Find Full Text PDFNutr Health
December 2024
Biology and Environmental Science Department, University of New Haven, West Haven, CT, USA.
Folic acid (FA) supplementation is widely regarded as a key nutritional intervention during pregnancy due to its protective effect against neural tube defects. Recent research has reported FA supplementation outcomes on offspring's health, with increased incidences of allergy/respiratory problems. This study evaluates if increased levels of 5-methyltetrahydrofolate (5-MTHF) are associated with DNA modification, leading to disruption of cell proliferation in fetal lung cells and increasing susceptibility to asthma.
View Article and Find Full Text PDFPeerJ Comput Sci
November 2024
Solutions Architect AI, Fourien Inc., Alberta, Edmonton, Canada.
Climate change has become a major source of concern to the global community. The steady pollution of the environment including our waters is gradually increasing the effects of climate change. The disposal of plastics in the seas alters aquatic life.
View Article and Find Full Text PDFInteract J Med Res
November 2024
School of Health and Life Sciences, Glasgow Caledonian University, Glasgow, United Kingdom.
Background: Co-creation is increasingly recognized for its potential to generate innovative solutions, particularly in addressing complex and wicked problems in public health. Despite this growing recognition, there are no standards or recommendations for method use in co-creation, leading to confusion and inconsistency. While some studies have examined specific methods, a comprehensive overview is lacking, limiting the collective understanding and ability to make informed decisions about the most appropriate methods for different contexts and research objectives.
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