Background: Posttraumatic hydrocephalus (PTH) and posthemorrhagic hydrocephalus (PHH) were previously considered not suitable for neuroendoscopic treatment. New hydrocephalus theories support possible successful neuroendoscopy in such patients.
Methods: This study presents the results of neuroendoscopy in PTH and PHH with a background analysis. From 130 hydrocephalic patients after neuroendoscopic surgeries, 35 cases with PTH (n = 11) or PHH (n = 24; acute: n = 9, subacute: n = 10, chronic: n = 5) were found. The success rate (Glasgow Outcome Scale [GOS] score 4 or 5 without shunt) and clinical outcome (GOS score) of endoscopic third ventriculostomy (ETV) were analyzed. During the study period, 34 patients had ventriculoperitoneal shunts implanted, including 2 PTH and 5 PHH patients (all chronic).
Results: The success rate of ETV in PTH was 54.5%. In acute PHH, the success rate was 33.3%, 42.8% after excluding devastating hematomas. A post-ETV shunt was implanted in 1 patient (massive subarachnoid hemorrhage [SAH]) with final GOS score of 5. In subacute cases, the ETV success rate was 40% (no post-ETV shunts). In chronic PHH, only 1 patient with a GOS score of 5 was shunt-free (20%). The cause of ETV failure was massive SAH. Low final GOS score was caused by the extent of intracerebral bleeding or extracranial problems. The main indications for primary shunt implantation in PTH and PHH were infectious complications. The rate of good outcomes was 0% in PTH and 40% in PHH.
Conclusions: The best results of neuroendoscopy were achieved in PTH and acute PHH. ETV failures were associated with massive SAH; arachnoid cistern blockage and scarring precludes ETV success.
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http://dx.doi.org/10.1016/j.wneu.2018.01.186 | DOI Listing |
J Am Coll Cardiol
December 2024
Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Background: The growing use of leadless pacemaker (LP) technology requires safe and effective solutions for retrieving and removing these devices over the long term.
Objectives: This study sought to evaluate retrieval and removal of an active helix-fixation LP studied in worldwide regulatory clinical trials.
Methods: Subjects enrolled in the LEADLESS II phase 1 investigational device exemption, LEADLESS Observational, or LEADLESS Japan trials with an attempted LP retrieval at least 6 weeks postimplantation were included.
Vaccines (Basel)
December 2024
Laboratory of Molecular Studies and Experimental Therapy-LEMTE, Department of Genetics, Federal University of Pernambuco, Recife 50670-901, Brazil.
Background/objectives: DNA vaccines are rapidly produced and adaptable to different pathogens, but they face considerable challenges regarding stability and delivery to the cellular target. Thus, effective delivery methods are essential for the success of these vaccines. Here, we evaluated the efficacy of capsules derived from the cell wall of the yeast as a delivery system for DNA vaccines.
View Article and Find Full Text PDFSensors (Basel)
December 2024
Shanghai Research Institute of Microelectronics, Peking University, Shanghai 201203, China.
Despite the accuracy and robustness attained in the field of object tracking, algorithms based on Siamese neural networks often over-rely on information from the initial frame, neglecting necessary updates to the template; furthermore, in prolonged tracking situations, such methodologies encounter challenges in efficiently addressing issues such as complete occlusion or instances where the target exits the frame. To tackle these issues, this study enhances the SiamRPN algorithm by integrating the convolutional block attention module (CBAM), which enhances spatial channel attention. Additionally, it integrates the kernelized correlation filters (KCFs) for enhanced feature template representation.
View Article and Find Full Text PDFSensors (Basel)
December 2024
Deanship of Preparatory Year and Supporting Studies, Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia.
Effective monitoring of road conditions is crucial for ensuring safe and efficient transportation systems. By leveraging the power of crowd-sourced smartphone sensor data, road condition monitoring can be conducted in real-time, providing valuable insights for transportation planners, policymakers, and the general public. Previous studies have primarily focused on the use of pre-trained machine learning models and threshold-based methods for anomaly classification, which may not be suitable for real-world scenarios that require incremental detection and classification.
View Article and Find Full Text PDFSensors (Basel)
December 2024
Qualcomm, San Jose, CA 95110, USA.
With the development of Internet of Vehicles (IoV) technology, the need for real-time data processing and communication in vehicles is increasing. Traditional request-based methods face challenges in terms of latency and bandwidth limitations. Mode 4 in cellular vehicle-to-everything (C-V2X), also known as autonomous resource selection, aims to address latency and overhead issues by dynamically selecting communication resources based on real-time conditions.
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