AI Article Synopsis
- This study investigates how the combination of NT-pro-BNP levels and certain clinical factors can better predict cardiogenic pulmonary edema (CPE) in heart failure patients.
- A retrospective analysis of 269 adult heart failure patients identified key factors linked to CPE, leading to the creation of a new NT-pro-BNP-based diagnostic score for risk assessment.
- The findings suggest that this scoring system is effective in predicting CPE, potentially improving patient management in emergency situations.
Article Abstract
Background: Cardiogenic pulmonary edema (CPE) is a life-threatening emergency necessitating aggressive management. We conducted this study to test the hypothesis that a combination of N-terminal pro-b-type natriuretic peptide (NT-pro-BNP) and some relevant clinical factors may provide better predictability for CPE in heart failure (HF) patients.
Methods: This retrospective study enrolled adult HF patients hospitalized during January 2011 to December 2013. After determining the independent predictors for the occurrence of CPE, a novel NT-pro BNP-based diagnostic score for predicting CPE was established.
Results: A total of 269 patients (mean age, 74.5 ± 13.6 years; female, 53.9%) were enrolled, and categorized into CPE group (n = 80, 29.7%) and non-CPE group (n = 189, 70.3%). Several factors such as "Serum NT-pro-BNP level > 6980 mg/dl," "systemic blood pressure > 170 mm Hg," "heart rate > 120 bpm," "with rales in breathing sound," "with jugular vein engorgement," "with NYHA Fc III/IV," "with chronic lung disease" and "with angiotensin converting enzyme inhibitors/angiotensin receptor blocker" were found to be associated with the existence of CPE. A novel NT-pro BNP based scoring system containing these risk factors was proposed and proven excellent in predicting CPE.
Conclusions: The NT-pro-BNP scoring system could predict CPE in HF patients.
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| http://dx.doi.org/10.1016/j.cca.2018.01.042 | DOI Listing |
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