We report on a 50-year-old patient suffering from erythrodermic sarcoidosis accompanied by visible enlargement of the peripheric lymph nodes. Histologic examination revealed epithelioid granulomas in the skin, in a lymph node, and in a liver biopsy. Ultrastructurally, we found a focal presence of cells with Langerhans' granules sometimes in a spatial relation to lymphoid cells within the corial granulomas.
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Dermatol Reports
June 2023
Department of Dermatology and Venereology, Military Medical Academy, Sofia, Bulgaria.
Post-vaccinal and parainfectious activation of the immunity with subsequent development of a certain immunological/skinimmunological disease is not rare in clinical practice. This concept is mentioned in relation to molecular/antigenic mimicry. To this day, the pathogenesis of sarcoidosis and sarcoid-type reactions remains a mystery.
View Article and Find Full Text PDFJ Cutan Med Surg
December 2018
1 Department of Dermatology, Texas Tech Health Sciences Center, Lubbock, TX, USA.
Sarcoidosis is a multisystem inflammatory condition of unknown etiology. Variability in the cutaneous features of sarcoidosis is profound, and its protean manifestations affirm the condition's designation as one of dermatology's "great mimics." Cutaneous phenotypes of sarcoidosis include but are by no means limited to ichthyosiform, alopecic, erythrodermic, angiolupoid, and verrucous variants.
View Article and Find Full Text PDFAnn Dermatol
February 2017
Department of Dermatology, Chonbuk National University Medical School, Jeonju, Korea.; Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, Korea.
The development of cutaneous sarcoidosis as a paradoxical adverse event of tumor necrosis factor alpha (TNF-α) blockers has been reported in the literature; however, an erythrodermic form of cutaneous sarcoidosis during anti-TNF-α therapy has not yet been reported. Herein, we report the first case of an erythrodermic form of cutaneous sarcoidosis during anti-TNF-α therapy and review previous studies of cutaneous sarcoidosis. A 6-year-old Korean girl who had been suffering from juvenile rheumatoid arthritis presented with generalized erythematous skin eruption involving more than about 90% of her body surface area.
View Article and Find Full Text PDFAnn Dermatol Venereol
December 2015
Service de dermatologie-vénéréologie, CHU Mohammed VI, 40000 Marrakech, Maroc.
Background: The cutaneous signs of sarcoidosis are polymorphous and occasionally misleading. Herein, we report a rare case of profuse sarcoidosis involving various rare cutaneous signs specific to the disease associated with multiple cutaneous squamous cell carcinomas.
Patients And Methods: A seventy-three-year-old man had been presenting dry ichthyosiform erythroderma for 2 years.
Clin Exp Dermatol
September 2003
Department of Dermatology, Hanyang University College of Medicine, Seoul, South Korea.
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