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The impact of a secondary, rare, non-pathogenic PKD1 variant on disease progression in autosomal dominant polycystic kidney disease.
J Nephrol
January 2025
Department of Nephrology, Beaumont Hospital, Dublin, Ireland.
Background: Autosomal dominant polycystic kidney disease (ADPKD) is caused primarily by pathogenic variants in the PKD1 and PKD2 genes. Although the type of ADPKD variant can influence disease severity, rare, hypomorphic PKD1 variants have also been reported to modify disease severity or cause biallelic ADPKD. This study examines whether rare, additional, potentially protein-altering, non-pathogenic PKD1 variants contribute to ADPKD phenotypic outcomes.
View Article and Find Full Text PDFOutcomes and efficacy of robotic-assisted radical prostatectomy using the CMR Versius platform: a prospective study on 118 patients with 1-year follow-up.
Int Urol Nephrol
January 2025
Department of Urology, Faculty of Medicine, Cairo University, Cairo, Egypt.
Objective: To evaluate the outcomes and efficacy of robot-assisted radical prostatectomy (RARP) using the Versius robotic surgical system, aiming to provide comprehensive data on perioperative outcomes, postoperative recovery, and complications.
Patient And Methods: All cases of RARP using the CMR Versius platform performed at Cairo University Hospital over a two-year period were enrolled in this study. All patients had pathologically confirmed prostate cancer in both localized and locally advanced stages.
Findings from trans-inclusive sexual health screening efforts.
Sex Transm Infect
January 2025
56 Dean Street, Soho, London, UK.
[Advances and challenges in the transsexualizing process in the Brazilian Unified Health System].
Cien Saude Colet
January 2025
Colegiado de Medicina, Universidade Federal do Vale do São Francisco. Av. da Amizade s/n, Bairro Sal Torrado. 48605-780 Paulo Afonso BA Brasil.
The implementation of the Transsexualizing Process (TP) / Gender-affirming Surgeries (GAS) in the Unified Health System (SUS) was the result of social struggles by the LGBT community for sexual rights, the construction of gender identity, and bodily autonomy. The scope of this article is to analyze the advances and challenges of TP/GAS in the SUS, through a qualitative narrative literature review. In June 2022, searches were conducted in the Google Scholar, SciELO, and VHL databases to select scientific articles in Portuguese published in the last 10 years, excluding articles in foreign languages and other types of academic work such as reviews, undergraduate theses, dissertations, and/or graduate theses.
View Article and Find Full Text PDFDifferent measures of fundamental frequency and vocal satisfaction among transgender men and women.
Codas
January 2025
Departamento de Saúde Interdisciplinaridade e Reabilitação, Faculdade de Ciências Médicas, Universidade Estadual de Campinas - UNICAMP - Campinas (SP), Brasil.
Purpose: To verify possible correlations between fo and voice satisfaction among Brazilian transgender people.
Methods: An observational, cross-sectional quantitative study was conducted with the Trans Woman Voice Questionnaire (TWVQ), voice recording (sustained vowel and automatic speech) and extraction of seven acoustic measurements related to fo position and variability in transgender people. Participants were divided into two groups according to gender.
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