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Revisiting Factors Influencing Under-Five Mortality in India: The Application of a Generalised Additive Cox Proportional Hazards Model.
Int J Environ Res Public Health
September 2024
Department of Biostatistics, All India Institute of Medical Sciences, New Delhi 110029, India.
Article Synopsis
- India faces a high under-five mortality rate (U5MR) despite preventive measures, prompting a study that uses advanced statistical methods to examine contributing factors.
- The analysis, based on data from over 213,000 children in the National Family Health Survey (NFHS-5), reveals that shorter pregnancy lengths significantly increase U5MR risk, and factors like maternal age, hemoglobin levels, education, and household wealth also play crucial roles.
- The study suggests that improving maternal and socioeconomic conditions, alongside healthcare access, is vital for reducing U5MRs, advocating for approaches that consider complex relationships among these factors.
Protoporphyrin IX iron(II) revisited. An overview of the Mössbauer spectroscopic parameters of low-spin porphyrin iron(II) complexes.
J Biol Inorg Chem
December 2024
Department of Chemical Engineering, Wolfson Centre for Sustainable Materials Processing and Development, Brunel University of London, Kingston Lane, Uxbridge, Middlesex, UB8 3PH, UK.
Mössbauer parameters of low-spin six-coordinate [Fe(II)(Por)L] complexes (where Por is a synthetic porphyrin; L is a nitrogenous aliphatic, an aromatic base or a heterocyclic ligand, a P-bonding ligand, CO or CN) and low-spin [Fe(Por)LX] complexes (where L and X are different ligands) are reported. A known point charge calculation approach was extended to investigate how the axial ligands and the four porphyrinato-N atoms generate the observed quadrupole splittings (ΔE) for the complexes. Partial quadrupole splitting (p.
View Article and Find Full Text PDFRevisiting Physiological and Operative Severity Score for the Enumeration of Mortality and Morbidity (POSSUM) and Portsmouth-POSSUM (P-POSSUM) Scores: Are They Valid in Cases of Ileal Perforation?
Cureus
July 2024
General Surgery, Topiwala National Medical College & B. Y. L. Nair Charitable Hospital, Mumbai, IND.
Introduction Ileal perforation due to typhoid is common in tropical countries, and the ensuing secondary peritonitis is treated by resuscitation and surgery. The Physiological and Operative Severity Score for the Enumeration of Mortality and Morbidity (POSSUM) was developed to predict postoperative outcomes to overcome systemic obstacles in any healthcare setup and is considered fairly accurate. The Portsmouth-POSSUM (P-POSSUM) score was developed as a corrective scoring system for overestimations made by the POSSUM score vis-à-vis mortality.
View Article and Find Full Text PDFRevisiting the full blood count: Circulating blood cells and their role in coagulation.
Br J Haematol
October 2024
Department of Clinical Infection, Microbiology and Immunology, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.
There has been an expansion in our understanding of the multifaceted roles of circulating blood cells in regulating haemostasis and contributing to thrombosis. Notably, there is greater recognition of the interplay between coagulation with inflammation and innate immune activation and the contribution of leucocytes. The full blood count (FBC) is a time-honoured test in medicine; however, its components are often viewed in isolation and without consideration of their haemostatic and thrombotic potential.
View Article and Find Full Text PDFRenal function as an effect modifier of intensive glucose control in delaying cognitive function decline among individuals with type 2 diabetes: A revisit to the ACCORD MIND trial.
Diabetes Obes Metab
September 2024
Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Aim: Dysglycaemia accelerates cognitive decline. Intensive glucose control may help delay or prevent cognitive function decline (CFD). We aimed to determine how patient characteristics influence the effect of intensive glucose control [glycated haemoglobin (HbA1c) <6.
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